DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment osp and aldh3b2

DIOPT Version :9

Sequence 1:	NP_001162975.1	Gene:	osp / 34850	FlyBaseID:	FBgn0003016	Length:	1566	Species:	Drosophila melanogaster
Sequence 2:	NP_001120622.1	Gene:	aldh3b2 / 100145787	XenbaseID:	XB-GENE-5776192	Length:	469	Species:	Xenopus tropicalis

Alignment Length:	275	Identity:	58/275 - (21%)
Similarity:	92/275 - (33%)	Gaps:	81/275 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   301 TVSMGGQDENNRNAGNEITN---RVS------QPTTCLLIEDIRRDEKT----IKDIANTITNLS 352
            |:.:||::....:...:|:|   |:|      ...|||..:.:...|:|    :|.:..|:....
Frog   208 TLELGGKNPCYVDEECDISNAARRISWSRYFNAGQTCLAPDYVLCTERTRDRLVKALKATVREFY 272

  Fly   353 QQQNKRWSTAVNNALNNQHHFGHHSQYQVTSRDETDFQMSSNSSSTKSQNPASER---PKSLPLA 414
            .|..|: |..:...:|:: ||...|..           :||.:..|..|...:|:   |..|...
Frog   273 GQDPKQ-SPDLGRIINDR-HFRRVSAL-----------LSSGTIVTGGQTDEAEKYIAPTILIDV 324

  Fly   415 SNSTPAIVSAIVKKIPTVMEQG----------DKTKPTARLQLHLKSPKHYQHERGDPDGGCNLD 469
            ..|.|.:...|...:..||..|          .:.:|.|......||....:...|...||
Frog   325 KESDPVMQEEIFGPVLPVMTIGGLDAALEFINKRERPLAAYVYSSKSQVVDRFLEGTSSGG---- 385

  Fly   470 ELCVNYMAKTDELRS----------VGKANSK--------------SSSGQGK------PPVKEE 504
             .|.|.......|.|          :||.:.|              .|.|:.|      ||..|:
Frog   386 -FCANDGLLHSTLISLPFGGIGHSGMGKYHGKFSFDTFSHHRACLLRSDGREKLNEIRYPPYTEQ 449

  Fly   505 -------SLNAKKGW 512
                   ::..||||
Frog   450 HLGMAVYAMEVKKGW 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
osp	NP_001162975.1	PH_RIP	48..191	CDD:269942
		PH	85..185	CDD:278594
		PH_M-RIP	509..613	CDD:270094	4/4 (100%)
		PH	509..603	CDD:278594	4/4 (100%)
		SbcC	726..1353	CDD:223496
aldh3b2	NP_001120622.1	ALDH_F3AB	5..447	CDD:143450	53/256 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165164121
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930