Protein Alignment ppk and scnn1b

DIOPT Version :9

• Sequence 1: NP_477232.1
• Gene: ppk / 34843
• FlyBaseID: FBgn0020258
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_001072437.1
• Gene: scnn1b / 779891
• XenbaseID: XB-GENE-949109
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 674
• Identity: 137/674 - (20%)
• Similarity: 229/674 - (33%)
• Gaps: 213/674 - (31%)

  Fly    52 RIRYGSPLSACKGLLLEYAKSTTIHGIRYIFEVHRPIYEKLYWLFFTCISVYFAVSLIWD----- 111
            ||:.| |....|.||:.:..:|..||.:.|  :.....:::.|...|.:   ||..:.|.
 Frog    19 RIQKG-PGYTYKELLVWFCDNTNTHGPKRI--IKEGPKKRVMWFILTLV---FAGLVFWQWGVLI 77

  Fly   112 -TYLKWQES-PVILGFDETLVPVHKIPFPTITIC-----------PEIK---------MER---- 150
             |||.:..| .:.:||       ..:.||.:|:|           |.:|         ::|
 Frog    78 LTYLSYGVSVSLSIGF-------KTMEFPAVTVCNANPYKYSRVKPLLKDLDALVATALDRIQFS 135

  Fly   151 -----NVFDYTNVSRQ------LWEE-------------------------YKQNGNISDLDDED 179
                 |.|..::.::.      ||..                         |.:|.:..:..::.
 Frog   136 SQDQANTFTQSSTNQNVTLDPTLWNHIPLVVIDETDPSNPIVNNIFDNNAIYSKNNSFRNSSEDQ 200

  Fly   180 LA---RMAVAMHICDSE----VVQRFTP--------LLSQLNP--PNVDVTQTLI------DLSI 221
            .:   |..|||.:|.:.    |.:.||.        .|.||:.  .||.:...:.      ||.:
 Frog   201 TSYSQRYKVAMKLCTNNNTQCVYRNFTSGIQALQEWYLLQLSSIFSNVPLADRIAMGFKAEDLIL 265

  Fly   222 SKNETGPFCKWNGRFYFCDKIFDFVATDEGICYQFN-GLRPKDIYRDEKFISYVDPDVVDFNKYF 285
            :....|..|.:..    ..:|:|   .|.|.||.|| |...:|.      ::..:|. .||....
 Frog   266 TCLFGGQPCSYRN----FTRIYD---ADYGNCYIFNWGQEGEDP------MASANPG-ADFGLKL 316

  Fly   286 DVDLPPWNNITGNWSLDTGFVDQGQN-AYPQRTVFSSVKNGFFAFLQGLQHNFDYDCRSFKQGYK 349
            .:|                 ::||:. .|.|.|..:                            :
 Frog   317 VLD-----------------IEQGEYLPYVQTTAAA----------------------------R 336

  Fly   350 VFLNSPESVPLTTGNYILVPHGDEVLVSVLPAYVVSTDNLHEITPEKRQCLFDDE----RSL--R 408
            :.|:...|.|......|....|.|..::||      .|.|..:......|..:..    ::|  .
 Frog   337 LILHQQRSFPFVKDLGIYAMPGTETSIAVL------VDQLEHMEAPYSSCTVNGSDIPVQNLYAE 395

  Fly   409 FFRSYSQSNCQTECLANYTVSKCGCAKFWMPKPLGTPVCGLKD-----INCYTSAQDELYTLMQN 468
            |..|||..:|...|.....|..||||.:..|.|.|:..|. .|     :.||...:|
 Frog   396 FNSSYSIQSCLRSCYQEQMVQTCGCADYQYPLPNGSEYCS-NDKYPDWVPCYYGLRD-------- 451

  Fly   469 QTMAKSIDESVDITCNCMPACTSLEYNFEISRAKYDVAKT------IRAFREEYEHTDAIGS--- 524
                 |:.:.......|...|...:|...||.|.:..|..      :.::.::..|...:..
 Frog   452 -----SVADRESCISLCQQPCNDTQYKMVISMADWPSAGAQDWIFHVLSYEKDSSHNITVNRNGI 511

  Fly   525 -RLSVYFKEHQFTAIKRTILFGVSTLISNCGGICGLFMGISCLSFLEL-------IYFFCMRICG 581
             ||::||:|..:.:|..:....|..|:||.||..|.:||.|.|..:|.       ::...:::..
 Frog   512 VRLNIYFQEFNYRSITESEATNVVWLLSNLGGQFGFWMGGSVLCIIEFGEIIIDCVWITILKLLA 576

  Fly   582 SCRDRRKHKIQQQNSVDLPEEKSE 605
            ..:|||:.: |:....|.|...||
 Frog   577 WIKDRRQRR-QRAQYADPPPTVSE 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:279230	122/624 (20%)
scnn1b	NP_001072437.1	ENaC	27..632	CDD:273304	133/665 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48391
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920