Protein Alignment ppk and Asic5

DIOPT Version :9

• Sequence 1: NP_477232.1
• Gene: ppk / 34843
• FlyBaseID: FBgn0020258
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_067345.1
• Gene: Asic5 / 58170
• MGIID: 1929259
• Length: 495
• Species: Mus musculus
• Alignment Length: 559
• Identity: 120/559 - (21%)
• Similarity: 195/559 - (34%)
• Gaps: 181/559 - (32%)

  Fly    68 EYAKSTTIHGIRYIFEVHRPIYEKLYWLFFTCISVYFAVSLIWD------TYLKWQESPVILGFD 126
            ::|.||:.|||..|.:....: .|:.||.....||..   |:|.      .|..|..:..|
Mouse    40 DFAMSTSFHGIHNIAQNQNKV-RKVIWLAVVLGSVSL---LVWQIYSRLVNYFTWPTTTSI---- 96

  Fly   127 ETLVPVHKIPFPTITICPEIKMERNVFDYTNVSRQLWEEYKQNGNISDLDDEDLARMAVAMHICD 191
             .:..|.||.||.:|:|                           |::....|.::|..:...:.|
Mouse    97 -EVQYVEKIEFPAVTLC---------------------------NLNRFQTEAVSRFGIIFFLWD 133

  Fly   192 --SEVVQRFTPLLSQLNPPNVDVTQTLIDLSISKN-ETGPFCKWNGRFYF-------CD------ 240
              |:|::     |.:::..|....:||..::..:| ....|.|.|| ||.       |:
Mouse   134 IVSKVLR-----LQEISANNTGSPETLDFVTNHQNFSITEFVKNNG-FYLNNDTLVHCEFFGKTC 192

  Fly   241 --KIFDFVATDEGICYQFN----------------GLR-PKDIYRDEKFISYVDPDVVDFNKYFD 286
              |.|..|.|:.|.|:.||                ||: ..|::::|               :.|
Mouse   193 SPKDFKHVFTEYGNCFTFNYGENIQNKNKVSVSGRGLKLLLDVHQEE---------------FTD 242

  Fly   287 VDLPPWNNITGNWSLDTGFVDQGQNAYPQRTVFSSVKNGFFAFLQGLQHNFDYDCRSFKQGYKVF 351
            ..:|             ||.|.|       .:|                               .
Mouse   243 NPVP-------------GFADAG-------VIF-------------------------------V 256

  Fly   352 LNSPESVPLTTGNYILVPHGDEVLVSVLPAYVVSTDNLHEITPEKRQCLFDDERSLRFFRSYSQS 416
            ::||:..|...|..:..|.|....|::.....|     |:..| ..:|  :....||.|.:||..
Mouse   257 IHSPKKEPQFDGLGLSSPVGMHARVTIRQLKTV-----HQEYP-WGEC--NPNIKLRNFITYSTY 313

  Fly   417 NCQTECLANYTVSKCGCAKFWMPKPLGTPV-CGLKD-INCYTSAQDELYTLMQNQTMAKSIDESV 479
            .|..||.|.:....|||..|.:|   |..| |.|.: .||.:...|.:        ..|.:....
Mouse   314 GCLKECKARHIQRLCGCLPFLLP---GNGVECDLLEYYNCVSPILDHI--------ERKGLCTMG 367

  Fly   480 DITCNCMPACTSLEY-------NFEISRAKYDVAKTIRAFREEYEHTDAIGSRLSVYFKEHQFTA 537
            ....:|..:|...||       .|...||...:||.:.. .:||...:.:...::.....::.|.
Mouse   368 THNSSCPVSCEETEYPATVSYSTFPSQRATRFLAKKLNQ-SQEYIRENLVNIEINYSDLNYKITQ 431

  Fly   538 IKRTILFGVSTLISNCGGICGLFMGISCLSFLELI-YFF 575
            .::.:  .|..|:::.||..|||.|.|.::.:|:| |||
Mouse   432 QQKAV--SVPELLADVGGQLGLFCGASLITIIEIIEYFF 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:279230	117/555 (21%)
Asic5	NP_067345.1	ASC	41..466	CDD:366339	117/554 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837899
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I5086
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.800