Protein Alignment ppk and asic2

DIOPT Version :10

• Sequence 1: NP_477232.1
• Gene: ppk / 34843
• FlyBaseID: FBgn0020258
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: XP_005164179.1
• Gene: asic2 / 407669
• ZFINID: ZDB-GENE-040513-4
• Length: 564
• Species: Danio rerio
• Alignment Length: 665
• Identity: 138/665 - (20%)
• Similarity: 218/665 - (32%)
• Gaps: 215/665 - (32%)

  Fly     7 DEEEKKSGISILPGPELLALPGFDTRASIASAALSDVPSDVIIKSR-IRYGSPLSACKGLLLEYA 70
            ||..:.:.::.|..  |:||.|...|.:      |..|.....:.| .|.|:|......|.:...
Zfish    12 DEAVRPAALAALWA--LMALEGRCLRPA------SPTPGQRRARRRHTRPGTPRDDLSRLTVALL 68

  Fly    71 KSTTIHGIRYIFEVHRPIYEKLYWL--FFTCISVYFAVSLIWDT--YLKWQESPVILGFDETLVP 131
            ..|.:||:|:|......:..:.:|:  |.||:.:.    |.|.:  .|.|...|       |...
Zfish    69 SRTRLHGLRHICSPSNSLSRRAFWMIAFCTCLGLL----LSWSSNRLLHWLAFP-------THTR 122

  Fly   132 VH-----KIPFPTITICPE----------------------IKMERN----VFDYTNVSRQLWEE 165
            ||     ::.|||:|||..                      :...|.    |.|.....|:.|
Zfish   123 VHTEWAKELAFPTVTICNNNPVRLYHLTKSDLYFAGHWLGLLLANRTARPLVLDLLQDDRRGW-- 185

  Fly   166 YKQNGNISDLDDEDLARMAVAMHICDSEVVQRFTPLLSQLNPPNVDVT---------QTLIDLSI 221
                  .|.|.|..|                 |.|      |...:.|         ..|.|:.:
Zfish   186 ------FSKLSDFRL-----------------FLP------PRRFEGTSLEFMDRLGHQLEDMLL 221

  Fly   222 SKNETGPFCKWNGRFYFCDKIFDFVATDEGICYQFNGLRPKDIYRDEKFISYVDPDVVDFNKYFD 286
            :       ||:.|....... |..|.|..|.||.||.
Zfish   222 A-------CKYRGEPCGAHN-FSTVFTRYGKCYMFNA---------------------------- 250

  Fly   287 VDLPPWNNITGNWSLDTGFVDQGQNAYPQRTVFSSVKNGFFAFLQGLQHNF-----DYDCRSFKQ 346
                               .::|:..  :.|:.....||....|...|..:     :.:..:|:.
Zfish   251 -------------------AEEGKTL--RTTMKGGTGNGLEIMLDIQQDEYLPVWGETEETAFEA 294

  Fly   347 GYKVFLNSPESVPLTTGNYILVPHGDEVLVSVLPAY--VVST--DNLHEITPEKRQCLFDDERSL 407
            |.:|.::|....|..          .|:...|.|.:  .|:|  ..|..:.|...:|:   .|:|
Zfish   295 GVRVQIHSQAEPPFV----------HELGFGVAPGFQTFVATQEQRLTYLPPPWGECV---SRAL 346

  Fly   408 --RFFRSYSQSNCQTECLANYTVSKCGCAKFWMP--KPLGTPVCGLKDINCYTSAQDELYTLMQN 468
              ..|:.||.|.|:.||...|.|..|.|...:||  .|..||               |.|.....
Zfish   347 DSGLFQVYSVSACRIECETRYIVENCNCRMVYMPGDSPYCTP---------------EQYKDCAE 396

  Fly   469 QTMAKSIDESVDITCNCMPACTSLEYNFEISRAKYDVAKTIRAFREEYEH-----TDAIGSRLSV 528
            ..:| ::.......|.|...|....||.|:|..|.....:.|...:::..     ||.| ..|.|
Zfish   397 PALA-ALSAVEGTNCICRSPCNMTRYNKELSMVKIPSKTSARYLEKKFNRSEKYITDNI-LVLDV 459

  Fly   529 YFKEHQFTAIKRTILFGVSTLISNCGGICGLFMGISCLSFLELIYFFCMRICGSCRDRRKHKIQQ 593
            :|:...:..|::...:.|:.|:.:.||..|||:|.|.|:.|||..:             .:::.:
Zfish   460 FFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTLLELFDY-------------AYEVVK 511

  Fly   594 QNSVDL--PEEKSEN 606
            :..:||  .||:.|:
Zfish   512 ERLLDLLNREEEEES 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:459966	118/566 (21%)
asic2	XP_005164179.1	ENaC	71..538	CDD:273304	123/598 (21%)