Protein Alignment ppk and scnn1a

DIOPT Version :9

• Sequence 1: NP_477232.1
• Gene: ppk / 34843
• FlyBaseID: FBgn0020258
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_001184124.1
• Gene: scnn1a / 395013
• XenbaseID: XB-GENE-996083
• Length: 633
• Species: Xenopus tropicalis
• Alignment Length: 580
• Identity: 126/580 - (21%)
• Similarity: 219/580 - (37%)
• Gaps: 135/580 - (23%)

  Fly    60 SACKGLLLEYAKSTTIHG-IRYIFEVHRPIYEKLYWLFF---TCISVYFAVSLIWDTYLKWQESP 120
            |:.:.|...:..:||||| ||.:......: :..:||..   |...:|:...|::..|..:   |
 Frog    17 SSYRELFEFFCSNTTIHGAIRLVCSRSNRM-KTAFWLVLFLATFGLMYWQFGLLFGQYFSY---P 77

  Fly   121 VILGFDETLVPVHKIPFPTITICPEIKMERNVFDYTNV-----------SRQLWEEYKQNGNISD 174
            |.:..:   |...|:|||.:|:|     ..|.:.|..:           .|.|:|.||.|..
 Frog    78 VSINLN---VNSDKLPFPAVTVC-----TLNPYRYKAIQNDLQELDKETQRTLYELYKYNST--- 131

  Fly   175 LDDEDLARMAVAMHICDSEVVQR---FTPLLSQLNPPNVD---VTQTLI--DLSISKNETGPFCK 231
                     .|...|..::.|:|   ..|.|.:|.||...   |::::|  :|.:.:.|
 Frog   132 ---------GVQGWIPTNQRVRRDRPGLPHLLELVPPGSKTHRVSRSVIEEELQVKRRE------ 181

  Fly   232 WNGRFYFCDKIFDFVATDEGICYQFNGLRPKDIYRDEKFISYVD-----PD--VVD--------- 280
            ||..|..|::       ..|.|:........|..|:.....|::     |:  .:|
 Frog   182 WNIGFKLCNE-------TGGDCFYQTYTSGVDAIREWYRFHYINILARVPEEAAIDGEQLENFIF 239

  Fly   281 ---FNK---------YFDVDLPPWNNITGN-WSLDTGFVDQGQNAYPQRTVFSS----VKNGFFA 328
               ||:         :|.      :.|.|| ::.:       ||...|..::||    :|||...
 Frog   240 ACRFNEESCTKANYSHFH------HAIYGNCYTFN-------QNRSGQSNLWSSSMPGIKNGLTL 291

  Fly   329 FLQGLQHNFDYDCRSFKQGYKVFLNSPESVPLTTGNYILVPHGDEVLVSVLPAYVVSTDNLHEIT 393
            .|:..||:: ....|...|.:|.::..:.......:...:|.|.|..:.      :..:.::.:.
 Frog   292 ILRTEQHDY-IPLLSSVAGARVLVHGHKEPAFMDDSGFNIPPGMETSIG------MKKETVNRMG 349

  Fly   394 PEKRQCLFD----DERSLRFFRSYSQSNCQTECLANYTVSKCGCAKFWMPKPLGTPVCGLKDINC 454
            .:...|..|    |.::| |...|::..|...|.....|.:|||...:.|...|...|   |.|.
 Frog   350 GKYSDCSEDGSDVDVKNL-FESEYTEQVCVRSCFQAAMVERCGCGYAFYPLSPGDEFC---DYNK 410

  Fly   455 YTSAQDELYTLMQNQTMAKSIDESVDITC--NCMPACTSLEYNFEISRAKYD--VAK--TIRAFR 513
            :.|.....|.|:...|..|       :.|  .|...|...||......:|:.  |::  ......
 Frog   411 HKSWGHCYYKLIIEFTSNK-------LGCFSKCRKPCLVSEYQLTAGYSKWPNRVSQDWVFHTLS 468

  Fly   514 EEYEHTDAIG-SRLSVYFKEHQFTAIKRTILFGVSTLISNCGGICGLFMGISCLSFLELI 572
            .:|..||..| ::|::||:|..:..|:.:....:..|:|..|....|:.|.|.||.:|::
 Frog   469 RQYNLTDRNGIAKLNIYFEELNYKTIQESPTINMVMLLSLLGSQWSLWFGSSVLSVVEML 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:279230	124/571 (22%)
scnn1a	NP_001184124.1	ENaC	18..602	CDD:273304	125/579 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	117	1.000	Domainoid score	I5830
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	117	1.000	Inparanoid score	I4647
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48391
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.060