DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk and ppk16

DIOPT Version :9

Sequence 1:	NP_477232.1	Gene:	ppk / 34843	FlyBaseID:	FBgn0020258	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	NP_001334673.1	Gene:	ppk16 / 3885612	FlyBaseID:	FBgn0065108	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	525	Identity:	129/525 - (24%)
Similarity:	215/525 - (40%)	Gaps:	76/525 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 YAKSTTIHGIRYIFEVHRPIYEKLYWLFFTCISVYFAVSLIWDTYLKWQESPVILGFDETLVPVH 133
            |.::|::||..||.......:|:.:||....:::..::.|:..::...||:|.:...:.:..|..
  Fly    59 YCQTTSLHGFSYITRQDISRHERWFWLVVVILAIITSIVLVVVSWYWSQETPTVTVIESSHFPTW 123

  Fly   134 KIPFPTITICPEIKMER----NVFDYTNVSRQLWEEYKQNGNISDLDD-EDLARMAVAMHICDSE 193
            .||||.:|||...|:.:    ::.|...|...:        |.|:|.: .:|..:.|...| .::
  Fly   124 NIPFPAVTICNFNKISKSKALSLLDQMQVPVGI--------NRSELHNLFNLTLLPVDTMI-SND 179

  Fly   194 VVQRFTPLLSQLNPPNVDVTQTLIDLSISKNETGPFCKWNGRFYFCDKIFDFVATDEGICYQFN- 257
            .:|::..:|| ||  |:.:.:....||....|....|.|.|....|:.:|..:.|.||.|..||
  Fly   180 SLQKYDRILS-LN--NLTLNRLTQQLSPDCIEMISSCIWKGINTRCESLFQRIDTMEGQCCTFNY 241

  Fly   258 --GLRPKDIYRDEKFISYVDPDVVDFNKYFDVDLPPWNNITGNWSLDTGFVDQGQNAYPQRTVFS 320
              |            ||...|:.:    .:.|...|: .:||             ..||  |..|
  Fly   242 FGG------------ISNNFPEKI----AYQVPKRPY-RVTG-------------CGYP--TGLS 274

  Fly   321 SVKNGFFA-----FLQGLQHNFDYDCRSFKQGYKVFLNSPESVPLTTGNYILVPHGDEVLVSVLP 380
            .:.|...:     |..|.             |:::.|:...:.|.......:|....|..|.:.|
  Fly   275 VLLNPMISDYYGTFFSGF-------------GFRLLLHDAYNFPDENSETKVVTTTRESFVRINP 326

  Fly   381 AYVVSTDNLHEITPEKRQCLFDDERSLRFFRSYSQSNCQTECLANYTVSKCGCAKFWMPKPLGTP 445
            ....:|:::..:....|.|||..|.::...|.||..||..||....||..|||...::.......
  Fly   327 ESTYATNDIRRMDLSLRNCLFGSEMTMHGLRRYSFINCMFECRVRMTVDLCGCLPPYVYNNGSYK 391

  Fly   446 VCGLKDINCYTSAQDELYTLMQNQTMAKSIDESVD-ITCNCMPACTSLEYNFEISRAKYDVAKTI 509
            |||:...||...::......:.|...:.||....| ..|.|:|.|.|..|..|.:..:.|:  :.
  Fly   392 VCGVLQTNCIIHSKRLFSHALANLNFSLSIVRETDSFPCGCLPDCQSNHYVSESTTGRLDI--SY 454

  Fly   510 RAFREEYEH-TDAIGSRLSVYFKEHQFTAIKRTILFGVSTLISNCGGICGLFMGISCLSFLELIY 573
            .|.|..:.: ||.|  .|.|:|.:...|..:..|.....:.:::.||:.||.||.|.::..|.||
  Fly   455 FANRPTFNNATDRI--LLHVFFSDLMSTRYRTDIFQNWLSALASFGGLLGLIMGFSIVTAFEFIY 517

  Fly   574 FFCMR 578
            |...|
  Fly   518 FLTFR 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:279230	126/519 (24%)
ppk16	NP_001334673.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456784
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000867
OrthoInspector	1	1.000	-	-		otm24766
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
	8	7.840