DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk and ppk27

DIOPT Version :9

Sequence 1:	NP_477232.1	Gene:	ppk / 34843	FlyBaseID:	FBgn0020258	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	NP_647826.2	Gene:	ppk27 / 38440	FlyBaseID:	FBgn0035458	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	548	Identity:	118/548 - (21%)
Similarity:	193/548 - (35%)	Gaps:	156/548 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 SRIRYGSPLSACKGLLLEYAKSTTIHGIRYIFEVHRPIYEKLYWLFFTCISVYFAVSLIWDTYLK 115
            |||     ::|....::||.:.|:::|...::.:.:...::::|..|....:.||...::...|:
  Fly     2 SRI-----VTAFNKTVVEYFRKTSLNGFGLLYFIRKRRIQRIFWFLFISFGILFASYAVFSMVLE 61

  Fly   116 WQESPVILGFDETLVPVHKIPFPTITICPEIKMERNVFDYTNVSRQLWE-EYKQNGNISDLDDED 179
            :.....|....|..|...:|.||.:.||...|     |.|.|:.....: ...||.::    |..
  Fly    62 FLSYSTIADLSELKVLEDEIHFPELKICSGYK-----FSYRNMLASAHDLVSSQNKSL----DYW 117

  Fly   180 LARMAVAMHICDSEVVQRFTPLLSQLNPPNVDVTQTLIDLSISKNETGPF-------------CK 231
            |.::::.....|:..|:          ..|||...:|:|:   ||.:...             ||
  Fly   118 LNKLSLLSGYFDALSVK----------AENVDDLNSLLDI---KNISSFLLALTPACESLILKCK 169

  Fly   232 WNGRFYFCDKIFDFVATDEGICYQFNGLRPKDIYRDEKFISYVDPDVVDFNKYFDVDLPPWNNIT 296
            .|.....|.|:|...|.::|.|.         :.|:                         :|:|
  Fly   170 LNNIPANCLKLFTLKAYNDGNCC---------VLRN-------------------------SNLT 200

  Fly   297 GNWSLDTGFVDQGQ-NAYPQRTVFSSVKNGFFAFLQGLQHNFDYDCRSFKQGYKVFLNSPESVPL 360
            |..:|   |:|..| :.||               |.|....|..                 .||.
  Fly   201 GELTL---FMDSSQIDEYP---------------LNGNLPGFSL-----------------HVPS 230

  Fly   361 TTGNYILVPHGDEVLVSVLPAYVVSTDNLHEITPEKRQCLFDDERSLRFFRSYSQSNCQTECLAN 425
            ..|...:.| |:...|.:....:.....|:|...|||.|.|..|       ..|:..|..||...
  Fly   231 WQGRVSINP-GEMAAVEIEVMELQGNSQLNEYAVEKRACYFSQE-------GESREKCLHECRIK 287

  Fly   426 YTVSKCGCAKF---WMPKPLGTPVCGLKDINCYTSAQDELYTLMQNQTMAKSIDESVDITC-NCM 486
            .|:..|.|..:   :..:..|  .|.|::|.|       |..:.:|.:.|:         | .|:
  Fly   288 ATLINCQCVPYPFEFRTQKFG--YCTLENIRC-------LQLVERNWSPAQ---------CPQCL 334

  Fly   487 PACTSLEYNFEISRAKYDVAKTIRAFREEYEHTDAIGSRLSVYFKEHQFTAIKRTILFGVSTLIS 551
            |.|..|.|               |..::...|.....|.|:..||.......|..||:....::|
  Fly   335 PLCNQLFY---------------RLNKQILGHLHPWRSELNFKFKTPHRQRYKTNILYHWYQMLS 384

  Fly   552 NCGGICGLFMGISCLSFLELIYFFCMRI 579
            |.||:.|:.:|.|.:|..|||||...|:
  Fly   385 NVGGVLGICIGCSFISGFELIYFLVFRL 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:279230	110/523 (21%)
ppk27	NP_647826.2	ASC	15..407	CDD:279230	110/523 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920