DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk and ppk6

DIOPT Version :9

Sequence 1:	NP_477232.1	Gene:	ppk / 34843	FlyBaseID:	FBgn0020258	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	NP_611461.3	Gene:	ppk6 / 37286	FlyBaseID:	FBgn0034489	Length:	498	Species:	Drosophila melanogaster

Alignment Length:	541	Identity:	115/541 - (21%)
Similarity:	203/541 - (37%)	Gaps:	128/541 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 EYAKSTTIHGIRYIFEVHRPI-YEKLYW----LFFTCISVYFAVSLIWDTYLKWQESPVILGFDE 127
            ||.:.|.:.|: ::...:|.. ..:..|    |....:|:|..: |:|   ||:...|::.....
  Fly    40 EYTERTKVSGM-WLMRRNRTYGLSRFIWSSVLLQLLLLSIYLTL-LLW---LKFYSYPILNTISN 99

  Fly   128 TLVPVHKIPFPTITIC-PEIKMERNVFDYTNVSRQLWEEYKQNGNISDLDDEDLARMAVAMHICD 191
            .| .:..:.||.:||| |::.....|..|.. :.::.:||            |:|.:.......:
  Fly   100 DL-SITDVAFPGVTICSPKVVNSERVDRYVK-TLKIPKEY------------DMAEVIAGFDFLN 150

  Fly   192 SEVVQRFTP----------LLSQLNPPNVDVTQTLIDLSISKNETGPFCKWNGRFYFCD---KIF 243
            :...|.|.|          .:.:||  ||.:.:..:.:|....:....|.|....:.|:   :..
  Fly   151 AFTDQSFEPPGHDSYRATDAVLRLN--NVSIWEAAMAVSPGCFDYVKRCFWGHTEFQCNQSHEYL 213

  Fly   244 DFVATDE--GICYQFNGLRPKDIYRDEKFISYVDPDVVDFNKYFDVDLPPWN-NITGNWSLDTGF 305
            .|:.|..  |.|..|| ..|    |:..|:                   |:: ||.|   :|.|.
  Fly   214 SFIPTTAYLGPCCSFN-YNP----RNASFV-------------------PFSANIFG---MDGGL 251

  Fly   306 VDQGQNAYPQRTVFSSVKNGFFAFLQGLQHNFDYDCRSFKQGYKVFLNSPESVPLTTGNYILVPH 370
            .                    |...:|.:.|.:       .|..|.::.|..........:.:..
  Fly   252 T--------------------FVGAEGSERNLN-------TGLIVLVHHPMDYVTEAAASVTITA 289

  Fly   371 GDEVLVSVLPAYVVSTDNLHEITPEKRQCLFDDERSLRFFRSYSQSNCQTECLANYTVSKCGCAK 435
            ..|..|.|.|....|:..:.|::..||.||...:..|   .:|.|:.|...|.....|.||||..
  Fly   290 QSESFVEVSPTVQSSSVEVLELSERKRDCLISGDLQL---SNYRQAACLLACQTEAIVKKCGCHP 351

  Fly   436 FWMPKPLGTPV--CGLKDINCYTSAQDELYTLMQNQTMAKSIDESVDITCNCMPAC-----TSLE 493
            :.:| .:|...  |.|.|..||::..|...::..:|               |:|.|     ::|.
  Fly   352 YLLP-IVGNKFKECNLNDTFCYSANYDNFKSVRCDQ---------------CLPNCYDVTYSTLS 400

  Fly   494 YNFEISRAKYDVAKTIRAFREEYEHTDAIGSRLSVYFKEHQFTAIKRTILFGVSTLISNCGGICG 558
            |..::::.||.|:   |.:..|..:.|:.  .|.||..:.....|::..:.....|:|:.|||..
  Fly   401 YKTDLNQHKYSVS---RFYSPELLNNDSF--VLRVYLAKQVVPVIRKVTVMSWIGLLSDLGGIFN 460

  Fly   559 LFMGISCLSFLELIYFFCMRI 579
            |.:|:|.:|.:|..|:...|:
  Fly   461 LCLGLSMISVVEFFYYCTYRL 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:279230	112/533 (21%)
ppk6	NP_611461.3	ASC	85..476	CDD:279230	103/487 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456722
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D112386at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
	6	5.850