Protein Alignment ppk and Scnn1g

DIOPT Version :9

• Sequence 1: NP_477232.1
• Gene: ppk / 34843
• FlyBaseID: FBgn0020258
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_058742.2
• Gene: Scnn1g / 24768
• RGDID: 3641
• Length: 650
• Species: Rattus norvegicus
• Alignment Length: 661
• Identity: 137/661 - (20%)
• Similarity: 228/661 - (34%)
• Gaps: 184/661 - (27%)

  Fly    49 IKSRIRYGSPL-----SACKGLLLEYAKSTTIHGIRYIFEVHRPIYEKLYWLFFTCISVYFAVSL 108
            ||::|:...|:     ...|.|:..|..:|..||.|.|. |.|....:|.|:.||..:|...:
  Rat     7 IKAKIKKNLPVRGPQAPTIKDLMHWYCMNTNTHGCRRIV-VSRGRLRRLLWIAFTLTAVALII-- 68

  Fly   109 IWDTYLKWQESPVILGFDETLVPV----HKIPFPTITICPEIKMERNVFDYTNVSRQLWEEYKQN 169
                   ||.:.::..|....|.:    .|:.||.:|||     ..|.:.|:.||..|
  Rat    69 -------WQCALLVFSFYTVSVSIKVHFQKLDFPAVTIC-----NINPYKYSAVSDLL------- 114

  Fly   170 GNISDLDDEDLARMAVAMHICDSEVVQRFTPLLSQL--NPPNVDVTQTLIDLSI-SKNETGPFCK 231
               :|||.|....:.....:.:|...:....:.|.|  .||..   ..||.|.: ::||.|
  Rat   115 ---TDLDSETKQALLSLYGVKESRKRREAGSMPSTLEGTPPRF---FKLIPLLVFNENEKG---- 169

  Fly   232 WNGRFYFCDKIFDFVATDEGICYQFNGLRPK-------------DIYRDEKFISY--VDPDVVDF 281
                     |..||          |.|.:.|             .::..:|.:.:  ...|..|.
  Rat   170 ---------KARDF----------FTGRKRKISGKIIHKASNVMHVHESKKLVGFQLCSNDTSDC 215

  Fly   282 NKY-FDVDLPPWNNITGNWSLDTGFVDQGQNAYPQRTVFSSVKNGFFA-------FLQGLQ---H 335
            ..| |...:    |....|     :.....|...|..:...:...:.|       |..|:.   .
  Rat   216 ATYTFSSGI----NAIQEW-----YKLHYMNIMAQVPLEKKINMSYSAKELLVTCFFDGMSCDAR 271

  Fly   336 NFDY-------DCRSF----------------KQGYKV--FLNSPESVPL---TTGNYILV---- 368
            ||..       :|.:|                :.|.:|  ::|..|..|.   :||..:|:
  Rat   272 NFTLFHHPMYGNCYTFNNKENATILSTSMGGSEYGLQVILYINEDEYNPFLVSSTGAKVLIHQQN 336

  Fly   369 --PHGDEVLVSVLPAYVVSTDNLH-----EITPEKRQCLFD--DERSLRFFR-SYSQSNCQTECL 423
              |..::|.:.:..|...|. .:|     :::....||..|  |......:. :||...|...|.
  Rat   337 EYPFIEDVGMEIETAMSTSI-GMHLTESFKLSEPYSQCTEDGSDVPVTNIYNAAYSLQICLYSCF 400

  Fly   424 ANYTVSKCGCAKFWMPKPLGTPVCGLKD----INCYTSAQDELYTLMQNQTMAKSIDESVDITCN 484
            ....|.|||||::..|.|.....|..:.    :.||       |.|.|     ..:.|.:.....
  Rat   401 QTKMVEKCGCAQYSQPLPPAANYCNYQQHPNWMYCY-------YQLYQ-----AFVREELGCQSV 453

  Fly   485 CMPACTSLEYNFEISRAK---------------YDVAKTIRAFREEYEHTDAIGSRLSVYFKEHQ 534
            |..:|:..|:....|.|:               :|.::.|   .::...||.  ::|.:::|:..
  Rat   454 CKQSCSFKEWTLTTSLAQWPSEASEKWLLNVLTWDQSQQI---NKKLNKTDL--AKLLIFYKDLN 513

  Fly   535 FTAIKRTILFGVSTLISNCGGICGLFMGISCLSFLELIYFFCMRICGSCRDRRKHKI-------Q 592
            ..:|..:....:..|:||.||..||:|..|.:..:|:|..|.:........|:.||.       |
  Rat   514 QRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIARRQWHKAKDWWARRQ 578

  Fly   593 QQNSVDLPEEK 603
            ...|.:.|..:
  Rat   579 TPPSTETPSSR 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:279230	124/598 (21%)
Scnn1g	NP_058742.2	ENaC	24..631	CDD:273304	133/644 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	577..628		3/13 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	111	1.000	Domainoid score	I6095
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	111	1.000	Inparanoid score	I4773
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8907
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.870