Protein Alignment ppk and Scnn1b

DIOPT Version :9

• Sequence 1: NP_477232.1
• Gene: ppk / 34843
• FlyBaseID: FBgn0020258
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_036780.1
• Gene: Scnn1b / 24767
• RGDID: 3640
• Length: 638
• Species: Rattus norvegicus
• Alignment Length: 621
• Identity: 126/621 - (20%)
• Similarity: 219/621 - (35%)
• Gaps: 145/621 - (23%)

  Fly    52 RIRYGSPLSACKGLLLEYAKSTTIHG-IRYIFEVHRPIYEKLYWLFFTCISVYFAVSLIW----- 110
            |::.| |....|.||:.|..:|..|| .|.|.|..:   :|..|...|.:   ||..:.|
  Rat    13 RLQKG-PGYTYKELLVWYCNNTNTHGPKRIICEGPK---KKAMWFLLTLL---FACLVCWQWGVF 70

  Fly   111 -DTYLKWQES-PVILGFDETLVPVHKIPFPTITICPEIKMERNVFDYTNVSRQLWEEYKQNGNIS 173
             .|||.|:.| .:.:||       ..:.||.:|:|     ..:.|.|:.|...|.:.||.   :.
  Rat    71 IQTYLSWEVSVSLSMGF-------KTMNFPAVTVC-----NSSPFQYSKVKHLLKDLYKL---ME 120

  Fly   174 DLDDEDLARMAVAMHICD--SEVVQRFTP--LLSQLNPPNVDVTQTLIDLSISKNET-GPFCKWN 233
            .:.|:.||..:...:...  :..:...||  |:.:.||.:..|.....|...|.|.. |..|...
  Rat   121 AVLDKILAPKSSHTNTTSTLNFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQ 185

  Fly   234 GRFYFCDKIFDFVATDEGIC---------------------YQFNGLRPKDI----YRDEKFI-- 271
            |    |.......:.:..:|                     ..|:.:.|:|:    |..::.|
  Rat   186 G----CKVAMRLCSANGTVCTFRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILA 246

  Fly   272 SYVDPDVVDFNKYFDVDLPPWNN-ITGNWSLDTGFVDQGQNAYPQ---------RTVFSSVKNGF 326
            .....:......:..:..|.:.| ...||.:.       :.|.|.         :.:....:..:
  Rat   247 CLFGTEPCSHRNFTPIFYPDYGNCYIFNWGMT-------EKALPSANPGTEFGLKLILDIGQEDY 304

  Fly   327 FAFLQGLQHNFDYDCRSFKQGYKVFLNSPESVPLTTGNYILVPHGDEVLVSVL--------PAYV 383
            ..||            :...|.::.|:...:.|......|....|.|..:.||        ..|.
  Rat   305 VPFL------------ASTAGARLMLHEQRTYPFIREEGIYAMAGTETSIGVLLDKLQGKGEPYS 357

  Fly   384 VSTDNLHEITPEKRQCLFDDERSLRFFRSYSQSNCQTECLANYTVSKCGCAKFWMPKPLGTPVCG 448
            ..|.|..::.   .|.|:.|     :..:||...|...|..::.:..|.|..:..|.|.|...|.
  Rat   358 PCTMNGSDVA---IQNLYSD-----YNTTYSIQACLHSCFQDHMIHNCSCGHYLYPLPAGEKYCN 414

  Fly   449 LKDI----NCYTSAQDELYTLMQNQTMAKSIDESVDITCNCMPACTSLEYNFEISRAKYDVAKT- 508
            .:|.    .||.|.|   .:::|.:|....          |..:|...:|...||.|.:....:
  Rat   415 NRDFPDWAYCYLSLQ---MSVVQRETCLSM----------CKESCNDTQYKMTISMADWPSEASE 466

  Fly   509 ---IRAFREEYEHTDAIG------SRLSVYFKEHQFTAIKRTILFGVSTLISNCGGICGLFMGIS 564
               :....:|.:.:..|.      .:|::||:|..:..|:.:....:..|:||.||..|.:||.|
  Rat   467 DWILHVLSQERDQSSNITLSRKGIVKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGFWMGGS 531

  Fly   565 CLSFLE-------LIYFFCMRICGSCRDRRKHKIQQ 593
            .|..:|       .|:...:::..||:..|:.:.|:
  Rat   532 VLCLIEFGEIIIDFIWITVIKLVASCKGLRRRRPQR 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:279230	116/583 (20%)
Scnn1b	NP_036780.1	ENaC	21..621	CDD:273304	123/612 (20%)
		deg-1	29..538	CDD:273309	114/573 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	598..620

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	111	1.000	Domainoid score	I6095
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	111	1.000	Inparanoid score	I4773
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8907
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.870