Protein Alignment ppk and Asic4

DIOPT Version :9

• Sequence 1: NP_477232.1
• Gene: ppk / 34843
• FlyBaseID: FBgn0020258
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: XP_036020902.1
• Gene: Asic4 / 241118
• MGIID: 2652846
• Length: 586
• Species: Mus musculus
• Alignment Length: 574
• Identity: 119/574 - (20%)
• Similarity: 187/574 - (32%)
• Gaps: 150/574 - (26%)

  Fly    57 SPLSACKGL-----LLEYAKSTTIHGIRYIFEVHRPIYEKLYWLFFTCIS----VYFAVSLIWDT 112
            |.|.|.:|.     |..:|.::|:||:............:..|......|    :|.|.||. ..
Mouse    28 SLLGAAQGPAAPRDLATFASTSTLHGLGRACGPGPHGLRRTLWALALLTSLAAFLYQAASLA-RG 91

  Fly   113 YLKWQESPVILGFDETLVPVHKIPFPTITICPEIKMERNVFDYTNVSRQLWEEYKQNGNISDLDD 177
            ||   ..|.::..|.. .|.....||.:|:|             |::|     ::.    |.|.|
Mouse    92 YL---TRPHLVAMDPA-APAPVAGFPAVTLC-------------NINR-----FRH----SALSD 130

  Fly   178 EDLARMAVAMHICDSEVVQRFTPLLSQLNPPNVDVT----QTLIDLSISKNETGPFCKWNGRFYF 238
            .|:..:|....:...:........|....|..||:.    ..|.|:..|.|.:|..|..:.
Mouse   131 ADIFHLANLTGLPPKDRDGHRAAGLRYPEPDMVDILNRTGHQLADMLKSCNFSGHHCSASN---- 191

  Fly   239 CDKIFDFVATDEGICYQFNGLRPKDIYRDEKFISYVDPDVVDFNKYFDVDLPPWNNITGNWSLDT 303
                |..|.|..|.||.||                .||
Mouse   192 ----FSVVYTRYGKCYTFN----------------ADP--------------------------- 209

  Fly   304 GFVDQGQNAYPQRTVFSSVKNGFFAFLQGLQHNF-----DYDCRSFKQGYKVFLNSPESVPLTTG 363
                  |::.|.|.  ..:.:|....|...|..:     :.:..||:.|.:|.::|.|..|....
Mouse   210 ------QSSLPSRA--GGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQ 266

  Fly   364 NYILVPHGDEVLVSVLPAYVVSTDNLHEITPEKRQCLFDD---ERSLRFFRSYSQSNCQTECLAN 425
            ....|..|.:..||      .....|..:......|..:.   |..|:.:.:||.|.|:..|...
Mouse   267 LGFGVSPGFQTFVS------CQEQRLTYLPQPWGNCRAESELREPELQGYSAYSVSACRLRCEKE 325

  Fly   426 YTVSKCGCAKFWMPKPLGTPVCGLKDINCYTSAQDEL--------------------YTLMQNQT 470
            ..:.:|.|....||.....||.|...::..||.:...                    |..|.|:|
Mouse   326 AVLQRCHCRMVHMPGGHLQPVFGATLLSSRTSRRQRCMRTTCTRIYTHERVLMCMSGYLHMGNET 390

  Fly   471 MA------KSIDESVDI-------TCNCMPACTSLEYNFEISRAKYDVAKTIRAFREEYEHTDAI 522
            :.      :..|.::|.       .|.|...|....|..|||..|.....:.|....:|...:..
Mouse   391 ICPPNIYIECADHTLDSLGGGSEGPCFCPTPCNLTRYGKEISMVKIPNRGSARYLARKYNRNETY 455

  Fly   523 GSR----LSVYFKEHQFTAIKRTILFGVSTLISNCGGICGLFMGISCLSFLELI 572
            ...    |.|:|:.....|:::...:|:|.|:.:.||..|||:|.|.|:.||::
Mouse   456 IRENFLVLDVFFEALTSEAMEQQAAYGLSALLGDLGGQMGLFIGASILTLLEIL 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:279230	114/557 (20%)
Asic4	XP_036020902.1	ASC	40..535	CDD:413546	115/562 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I5086
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.960