Protein Alignment ppk and Scnn1a

DIOPT Version :9

• Sequence 1: NP_477232.1
• Gene: ppk / 34843
• FlyBaseID: FBgn0020258
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_035454.2
• Gene: Scnn1a / 20276
• MGIID: 101782
• Length: 700
• Species: Mus musculus
• Alignment Length: 612
• Identity: 125/612 - (20%)
• Similarity: 202/612 - (33%)
• Gaps: 211/612 - (34%)

  Fly    69 YAKSTTIHG-IRYIFEVHRPIYEKLYWLFFTCI--SVYFAVSLIWDTYLKWQESPVILGFDETLV 130
            :..:||||| ||.:...|..:....:.:.:.|.  .:|:..:|:::.|..:   ||.|..:   :
Mouse    88 FCNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFALLFEEYFSY---PVSLNIN---L 146

  Fly   131 PVHKIPFPTITIC-------PEIKMERNVFDYTNVSRQ-LWEEYKQNGNISDLDDEDLARMAVAM 187
            ...|:.||.:|:|       .|||.:....|  .::.| |::.||.|.:.:        |.|...
Mouse   147 NSDKLVFPAVTVCTLNPYRYTEIKEDLEELD--RITEQTLFDLYKYNSSYT--------RQAGGR 201

  Fly   188 HICDSEVVQRFT---------PLLSQLNPPNVDVTQTLIDLSISKNETGPFC---KWNGRFYFCD 240
                    :|.|         ||.....||..:..::....|.|..:..|..   .|...|..|:
Mouse   202 --------RRSTRDLRGALPHPLQRLRTPPPPNPARSARSASSSVRDNNPQVDRKDWKIGFQLCN 258

  Fly   241 KIFDFVATDEGICYQFNGLRPKDIYRDEKFISYVD-----PD---------------VVDFNK-- 283
            :       ::..|:........|..|:.....|::     ||               ...||:
Mouse   259 Q-------NKSDCFYQTYSSGVDAVREWYRFHYINILSRLPDTSPALEEEALGSFIFTCRFNQAP 316

  Fly   284 -----YFDVDLPPWNN-ITGNWSLDTGFVDQGQNAYPQRTVFSSVKNGFFAFLQGLQHNFDYDCR 342
                 |.....|.:.| .|.|         ...|:....:....|.||....|:..|::|
Mouse   317 CNQANYSQFHHPMYGNCYTFN---------NKNNSNLWMSSMPGVNNGLSLTLRTEQNDF----- 367

  Fly   343 SFKQGYKVFLNSPESVPL---TTGNYILVPHGD-------------------------EVLVSVL 379
                           :||   .||..::| ||.                         |.|.|:.
Mouse   368 ---------------IPLLSTVTGARVMV-HGQDEPAFMDDGGFNVRPGVETSISMRKEALDSLG 416

  Fly   380 PAYVVSTDNLHEITPEKRQCLFDDERSLRFFRSYSQSNCQTECLANYTVSKCGCAKFWMPKPLGT 444
            ..|...|:|..:: |.|.  |:..:        |:|..|...|.....:.|||||..:.|||.|.
Mouse   417 GNYGDCTENGSDV-PVKN--LYPSK--------YTQQVCIHSCFQENMIKKCGCAYIFYPKPKGV 470

  Fly   445 PVCG-LKDIN---CYTSAQDELYTLMQNQTMAKSIDESVDITCNCMPACT--------------- 490
            ..|. ||..:   ||...|           .|.|:| |:.....|...|:
Mouse   471 EFCDYLKQSSWGYCYYKLQ-----------AAFSLD-SLGCFSKCRKPCSVTNYKLSAGYSRWPS 523

  Fly   491 -----------SLEYNFEISRAKYDVAKTIRAFREEYEHTDAIGSRLSVYFKEHQFTAIKRTILF 544
                       ||:.|:.|:..:..|||                  |:::|||..:.....:...
Mouse   524 VKSQDWIFEMLSLQNNYTINNKRNGVAK------------------LNIFFKELNYKTNSESPSV 570

  Fly   545 GVSTLISNCGGICGLFMGISCLSFLEL 571
            .:.:|:||.|....|:.|.|.||.:|:
Mouse   571 TMVSLLSNLGSQWSLWFGSSVLSVVEM 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:279230	125/612 (20%)
Scnn1a	NP_035454.2	ENaC	80..677	CDD:273304	125/612 (20%)
		deg-1	88..600	CDD:273309	125/612 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820