Protein Alignment ppk and asic-1

DIOPT Version :9

• Sequence 1: NP_477232.1
• Gene: ppk / 34843
• FlyBaseID: FBgn0020258
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_491214.3
• Gene: asic-1 / 191422
• WormBaseID: WBGene00022815
• Length: 823
• Species: Caenorhabditis elegans
• Alignment Length: 831
• Identity: 144/831 - (17%)
• Similarity: 254/831 - (30%)
• Gaps: 356/831 - (42%)

  Fly    66 LLEYAKSTTIHGI--RYIFEVHRPIYEKLYWL--FFTCIS-----VYFAVSLIWDTYLKWQESPV 121
            ::::|:.|:.|||  .|:....|    :..||  |..|:|     .|..|.       ::..:.:
 Worm    14 VVDFAEHTSAHGIPRAYVSTGWR----RYMWLLCFLFCLSCFGHQAYLIVE-------RFNRNDI 67

  Fly   122 ILGFDETLVPVHKIPFPTITICPEIKMERNVFDYTN-VSRQLW------EEY-----KQNGN--- 171
            |:|.:   :...:|.||.:|||       |:..|.| .:|:|.      |.:     |.:||
 Worm    68 IVGVE---IKFEEIKFPAVTIC-------NMNPYKNSAARELGAIRNAIEAFELAIDKSDGNAHS 122

  Fly   172 ---------------------------------------------ISDLDDED------------ 179
                                                         :.|.||::
 Worm   123 KRKKRSANSKMVPIDLLCKEEHGMFTAHDYGHVECTCVTFEDMSKVGDTDDDEIFWNCHQRKDWT 187

  Fly   180 -----LARMAVAMHIC----DSEVVQRFTPLLSQLNPPNVDVTQTLIDLSISKNETGP------- 228
                 ||..:..:..|    |:.|....|   .||..| :.:::....|.||...:||
 Worm   188 HKICHLAEGSNQLKTCKCFEDTCVSDEVT---KQLVWP-LQLSKNGTKLCISPESSGPRYCASAQ 248

  Fly   229 --------FCKWNGRFYFCDKIFDFVATDE----------GICYQFNG-------------LRPK 262
                    .|.|.|:   |::..|....:|          |.|:|..|             :..:
 Worm   249 KFQVSTCSNCDWLGK---CEESDDMDLEEEIDSKTCICHHGNCFQIKGNVKKRKRRTPERKVHER 310

  Fly   263 DIYRDEKFI-----------------SYVDPDVVDFNK--------------------------- 283
            .:.|.|..:                 |..|.|:.:.||
 Worm   311 LLSRYEGLLAVYSHCNCTKQHGCVSTSVPDMDLENSNKTCLCFYNKKNEQIWPCYKEPEWEERKC 375

  Fly   284 ----------YFD--------------------VDLPPWNNITGNWSLDTGFV------------ 306
                      |.|                    :| ||..|.|   |||...|
 Worm   376 SRCNTMGDCVYSDKPKKQTISCLCATPIKMCVRID-PPQTNDT---SLDDRVVKFWDIQPSTTMS 436

  Fly   307 ------DQGQNAYPQRTV-------FSSVKNGFFAF-----------------------LQGLQH 335
                  ::...||....|       ..:::|..||.                       ..|.:.
 Worm   437 PIVKKKEERDKAYGYTGVKDRIALRAKAMENMIFAVDALTEEEKWKISYNKSDFIMKCSFNGREC 501

  Fly   336 NFDYD-----------CRSFKQ------------GY----KVFLNSPESVPLT--TGNYILV--- 368
            |..:|           |.::.|            .|    :||:|..|.:|.|  .|..:.|
 Worm   502 NVKHDFVEYLDPTYGACFTYGQKLGNNTNERSGPAYGLRLEVFVNVTEYLPTTEAAGVRLTVHAT 566

  Fly   369 ---PHGDEVLVSVLPAYV----VSTDNLHEITPEKRQCLFD--DERSLRFFRSYSQSNCQTECLA 424
               |..|.:..|....:|    :...::..:......|:.:  .|..:...::|:...||..|:.
 Worm   567 DEQPFPDTLGFSAPTGFVSSFGIKLKSMVRLPAPYGDCVREGKTEDFIYTQKAYNTEGCQRSCIQ 631

  Fly   425 NYTVSKCGCAKFWMPKPLGTPVCGLKDINCYTSAQDELYTLMQNQTMAKSIDESVDITCNCMPAC 489
            .:....|||.....|....:..|.:.|.......::|::...:         :|..:.|:|...|
 Worm   632 KHLSKTCGCGDPRFPPYRESKNCPVDDPYKRECIKNEMHVATR---------DSKKLGCSCKQPC 687

  Fly   490 TSLEYNFEISRAKY-----DVA---------KTIRAFREEYEHTDAIGSRLSVYFKEHQFTAIKR 540
            ....|:...|.:::     |::         ..:...||:       ||.:.|||::..:.::..
 Worm   688 NQDVYSVSYSASRWPAIAGDLSGCPLGMAAHHCLNYKREQ-------GSMIEVYFEQLNYESLLE 745

  Fly   541 TILFGVSTLISNCGGICGLFMGISCLSFLELIYFF---CMRICGSCRDRRK 588
            :..:|.|.|:|:.||..||:||:|.::..|:..||   .:.:..|.|.:|:
 Worm   746 SEAYGWSNLLSDFGGQLGLWMGVSVITIGEVACFFFEVFISLISSNRTKRR 796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:279230	139/809 (17%)
asic-1	NP_491214.3	deg-1	16..779	CDD:273309	139/810 (17%)
		ASC	17..>104	CDD:279230	27/107 (25%)
		ASC	<469..788	CDD:295594	61/334 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I4100
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820