Protein Alignment ppk and mec-10

DIOPT Version :9

• Sequence 1: NP_477232.1
• Gene: ppk / 34843
• FlyBaseID: FBgn0020258
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_509438.1
• Gene: mec-10 / 181101
• WormBaseID: WBGene00003174
• Length: 724
• Species: Caenorhabditis elegans
• Alignment Length: 706
• Identity: 126/706 - (17%)
• Similarity: 228/706 - (32%)
• Gaps: 232/706 - (32%)

  Fly    44 PSDVIIKSRIRYGSPLSACKGLLLEYAKSTTIHGIRYIFEVHRPIYEKLYWLFFTCI-SVYF--- 104
            |:.:..:.|||:.         |.::...|:.|||..:.:....:| :..|:|...| ::.|
 Worm    84 PTRLSYRERIRWH---------LQQFCYKTSSHGIPMLGQAPNSLY-RAAWVFLLLICAIQFINQ 138

  Fly   105 AVSLIWDTYLKWQE-SPVILGFDETLVPVHKIPFPTITIC-------PEIKMERNVFDYTNVSRQ 161
            ||::| ..|.|..: :.:.|.||..       |||.||:|       ..|:...::.....|.:.
 Worm   139 AVAVI-QKYQKMDKITDIQLKFDTA-------PFPAITLCNLNPYKDSVIRSHDSISKILGVFKS 195

  Fly   162 LWE----------------EYKQNG----------------------NISDLDDEDLARMAVAMH 188
            :.:                ||..||                      :..:.|:||      ..:
 Worm   196 VMKKAGDSSSEALEEEEETEYDMNGITIQAKRKKRGAGEKGTFEPANSACECDEED------GSN 254

  Fly   189 ICDSEVVQRFTPLLSQLNPPNVDVTQTLIDLSISKNETGP----------FCKWNGRFYFCDKIF 243
            .|:....::          |:.|....:.......|:..|          .|:.....|.|.|
 Worm   255 ECEERSTEK----------PSGDNDMCICAFDRQTNDAWPCHRKEQWTNTTCQTCDEHYLCSK-- 307

  Fly   244 DFVATDEGICYQFNGLRPKDIYRDEKFISYVDPD----VVDFNKYFDVDLPPWNNIT-------- 296
               ...:|.  :.:.|:.:....:.|.:..:..:    |::..:||. |...::.|:
 Worm   308 ---KAKKGT--KRSELKKEPCICESKGLFCIKHEHAAMVLNLWEYFG-DSEDFSEISTEEREALG 366

  Fly   297 -GNWSLDTGFVDQGQN---------AYPQRTVFSSVKNGFFAFLQGLQHN--------------- 336
             ||.:.:...|.:.:.         :..||.:.|..|:       .|.|.
 Worm   367 FGNMTDEVAIVTKAKENIIFAMSALSEEQRILMSQAKH-------NLIHKCSFNGKPCDIDQDFE 424

  Fly   337 ------------FDYDCRSFKQGYK----------VFLNSPESVP--------LTTGNYILVPHG 371
                        |::|...||...:          :|:|:.:.:|        ||..:....|..
 Worm   425 LVADPTFGNCFVFNHDREIFKSSVRAGPQYGLRVMLFVNASDYLPTSEAVGIRLTIHDKDDFPFP 489

  Fly   372 DEVLVSVLPAYVVS----TDNLHEITPEKRQCLFDDERSLRFFR--SYSQSNCQTECLANYTVSK 430
            |....|....|:.|    ...:..:......|:.|...|...::  :||...|...|.....:.:
 Worm   490 DTFGYSAPTGYISSFGMRMKKMSRLPAPYGDCVEDGATSNYIYKGYAYSTEGCYRTCFQELIIDR 554

  Fly   431 CGCAKFWMPKPLGTPVCGLKDINCYTSAQDELYTLMQNQTMAKSIDESVDI----TCNCMPACTS 491
            |||:....|...|...|             :::.....:.:.|...:..:|    .|.|...|..
 Worm   555 CGCSDPRFPSIGGVQPC-------------QVFNKNHRECLEKHTHQIGEIHGSFKCRCQQPCNQ 606

  Fly   492 LEYNFEISRAKY----------DVAKTIRAFREEYEHTDAIGSRLSVYFKEHQFTAIKRTILFGV 546
            ..|....|.|.:          ...|......|||:...|:   |.|:::...|..:..:..:|:
 Worm   607 TIYTTSYSEAIWPSQALNISLGQCEKEAEECNEEYKENAAM---LEVFYEALNFEVLSESEAYGI 668

  Fly   547 STLISNCGGICGLFMGIS--------CLSFLELIYFFCMRICGSCRDRRKHKIQQQ 594
            ..::::.||..||:.|:|        ||:| ||||   |.|.        |.|.||
 Worm   669 VKMMADFGGHLGLWSGVSVMTCCEFVCLAF-ELIY---MAIA--------HHINQQ 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:279230	114/659 (17%)
mec-10	NP_509438.1	ASC	88..723	CDD:295594	125/702 (18%)
		deg-1	99..696	CDD:273309	108/652 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I4100
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820