Protein Alignment ppk and unc-105

DIOPT Version :9

• Sequence 1: NP_477232.1
• Gene: ppk / 34843
• FlyBaseID: FBgn0020258
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_001364812.1
• Gene: unc-105 / 174306
• WormBaseID: WBGene00006832
• Length: 974
• Species: Caenorhabditis elegans
• Alignment Length: 713
• Identity: 128/713 - (17%)
• Similarity: 223/713 - (31%)
• Gaps: 217/713 - (30%)

  Fly    69 YAKSTTIHGIRYIFEVHRPIYEKLYWLFFTCISVYFAVSLIWDTYL--KWQESPVILGFDETLVP 131
            :.|.:|.|||.:.....    .|..|.::|..::.....||...:|  |:::....:..|   :.
 Worm   120 FEKQSTFHGISHAATAD----GKWRWFWYTAFTICLLALLIQIFFLISKYRQYGKTVDLD---LK 177

  Fly   132 VHKIPFPTITICPEIKMERNVFDYTNVSRQLWEEYKQNGNISDLDDEDLARMAV--AMH------ 188
            ....|||:||||.....:::.......::.:.|.|.:.....|..:...|.::.  .:|
 Worm   178 FENAPFPSITICNLNPYKKSAIQSNPNTKAMMEAYSRRIGSGDKTEGIAAALSATGGLHAKVRRA 242

  Fly   189 ---------ICDSEVVQRFTPLLSQLNPPNVDVTQTLID------------LSISKNETG----- 227
                     :.|....|.|...|       .|:.|...|            :.|..|.|.
 Worm   243 KRKAKGKPRLRDRRYHQAFAQCL-------CDIEQLTGDRKGSCFAAFKGKIEIDTNNTAGFMNL 300

  Fly   228 --------------------PFCKWNG---------------RFY----------------FCDK 241
                                |:..|..               |||                .|.|
 Worm   301 HTSRCLCQLDTVSKALWPCFPYSSWKEKLCSECVDNTGHCPMRFYKGNELYENIKEQVDLCLCHK 365

  Fly   242 IFDF-VAT-DEGICYQFNGLRPKDIYRD----EKFISYVDPDVVDFNKYFDVDLPPWNNITGNWS 300
            .::. |:| |:||..:   :.|.|...|    :|..|.:........:....:.|......|...
 Worm   366 EYNHCVSTRDDGIILE---ISPNDELNDLDIGKKIASQLSAQQEKQAEVTTTEAPTVTQALGFEE 427

  Fly   301 L--DTGFVDQGQNAYPQRTVFSSVKNGFFAF-------LQGLQHNFD------------------ 338
            |  |.....|.|            :|..||.       .:.:.:..|
 Worm   428 LTDDIAITSQAQ------------ENLMFAVGEMSEKAKESMSYELDELVLKCSFNQKDCQMDRD 480

  Fly   339 ----YD-----CRSF---------------KQGYKVFL--NSPESVP--------LTTGNYILVP 369
                ||     |.:|               ..|.:|.|  |..|.:|        :|..:..:||
 Worm   481 FTLHYDNTFGNCYTFNYNRTAEVASHRAGANYGLRVLLYANVSEYLPTTEAVGFRITVHDKHIVP 545

  Fly   370 HGDEVLVSV----LPAYVVSTDNLHEITPEKRQCLFDDERSLRFFRS---YSQSNCQTECLANYT 427
            ..|....|.    :.::.|.......:.|....|....|.:..|..:   ||...|...|.....
 Worm   546 FPDAFGYSAPTGFMSSFGVRMKQFIRLEPPYGHCRHGGEDAATFVYTGFQYSVEACHRSCAQKVI 610

  Fly   428 VSKCGCAKFWMPKPLGTPVCGLKDIN---CYTSAQDEL-----YTLMQNQTMAKSIDESVDITCN 484
            |..||||     .|: .||..:...|   |.....|:.     .||...:..:|. .|::...|.
 Worm   611 VEACGCA-----DPM-YPVAEMFGNNTKPCQAVNMDQRECLRNTTLWLGELYSKG-KEAIIPDCY 668

  Fly   485 CMPACTSLEYNFEISRAKY--DVAKTIRAF------REEYEHTDAIGSRLSVYFKEHQFTAIKRT 541
            |...|....|....|.|::  ..||.:...      .|:|....|:   :.::::|..:..::.:
 Worm   669 CHQPCQETNYEVTYSSARWPSGSAKVMECLPGDFLCLEKYRKNAAM---VQIFYEELNYETMQES 730

  Fly   542 ILFGVSTLISNCGGICGLFMGISCLSFLELIYFFCMRICGSCRDRRKHKIQQQNSVDLPEEKS 604
            ..:.:::::::.||:.||::|.|.:|.||::...........| :||..|..|:...:|..::
 Worm   731 PAYTLTSVLADLGGLTGLWIGASVVSLLEIVTLIVFATQAYVR-KRKGSISAQSHHSVPVHRA 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:279230	122/681 (18%)
unc-105	NP_001364812.1	deg-1	119..763	CDD:273309	122/681 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I4100
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	101	1.000	Inparanoid score	I3564
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.970