Protein Alignment ppk and Asic2

DIOPT Version :9

• Sequence 1: NP_477232.1
• Gene: ppk / 34843
• FlyBaseID: FBgn0020258
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: XP_006532059.1
• Gene: Asic2 / 11418
• MGIID: 1100867
• Length: 596
• Species: Mus musculus
• Alignment Length: 577
• Identity: 119/577 - (20%)
• Similarity: 192/577 - (33%)
• Gaps: 184/577 - (31%)

  Fly    73 TTIHGIRYI----------FEVHRPIYEKLYWLFFTCISVYFAVSLIWDTYLKWQESPVILGFDE 127
            |.:||:|::          |:      .:..|:...|.|:...:|...:..|.|...|
Mouse    64 TKLHGLRHMCAGRTAAGGSFQ------RRALWVLAFCTSLGLLLSWSSNRLLYWLSFP------- 115

  Fly   128 TLVPVHK-----IPFPTITICPEIKMERNVFDYTNVSRQLWEEYKQNGNISDLDDEDLARMAVAM 187
            :...||:     :|||.:|:|     ..|...:..:|:  .:.|.....:..|.....||
Mouse   116 SHTRVHREWSRQLPFPAVTVC-----NNNPLRFPRLSK--GDLYYAGHWLGLLLPNRTAR----- 168

  Fly   188 HICDSEVVQRFTPLLSQL---NPPNVDVTQTLIDLSISKNETGPFCKWNGRFYFCDKIFDFVATD 249
                        ||:|:|   :.|.....:.|.|.               |.:...:.|
Mouse   169 ------------PLVSELLRGDEPRRQWFRKLADF---------------RLFLPPRHF------ 200

  Fly   250 EGICYQFN---GLRPKDI-----YRDEKFISYVDPDVVDFNKYFDVDLPPWNNITGN-------- 298
            |||...|.   |.:.:|:     ||.|         :...:.:..|..||......:
Mouse   201 EGISAAFMDRLGHQLEDMLLSCKYRGE---------LCGPHNFSSVSCPPREPALSDPALPRSPE 256

  Fly   299 ---WSLDTG-------------FVDQGQNAYP-QRTVFSSVKNGFFAFLQGLQHNF-----DYDC 341
               |:..||             ..:.|::..| ..||.....||....|...|..:     :.:.
Mouse   257 ALRWAPGTGHQAPVFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEE 321

  Fly   342 RSFKQGYKVFLNSPESVPLTTGNYILVPHGDEVLVSVLPAY--VVST--DNLHEITPEKRQCLFD 402
            .:|:.|.||.::| :|.|         |...|:...|.|.:  .|:|  ..|..:.|...:|. .
Mouse   322 TTFEAGVKVQIHS-QSEP---------PFIQELGFGVAPGFQTFVATQEQRLTYLPPPWGECR-S 375

  Fly   403 DERSLRFFRSYSQSNCQTECLANYTVSKCGCAKFWMP-----------KPLGTPVCGL---KDIN 453
            .|..|.||..||.:.|:.:|...|.|..|.|....||           |....|..||   ||.|
Mouse   376 SEMGLDFFPVYSITACRIDCETRYIVENCNCRMVHMPGDAPFCTPEQHKECAEPALGLLAEKDSN 440

  Fly   454 CYTSAQDELYTLMQNQTMAKSIDESVDITCNCMPACTSLEYNFEISRAKYDVAKTIRAFREEYEH 518
                                        .|.|...|....||.|:|..|.....:.:...:::..
Mouse   441 ----------------------------YCLCRTPCNLTRYNKELSMVKIPSKTSAKYLEKKFNK 477

  Fly   519 TDAIGSR----LSVYFKEHQFTAIKRTILFGVSTLISNCGGICGLFMGISCLSFLEL 571
            ::...|.    |.::|:...:..|::...:.|:.|:.:.||..|||:|.|.|:.|||
Mouse   478 SEKYISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILEL 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk	NP_477232.1	ASC	69..574	CDD:279230	119/577 (21%)
Asic2	XP_006532059.1	ASC	64..590	CDD:383197	119/577 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I5086
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.970