Protein Alignment spel1 and MSH3

DIOPT Version :10

• Sequence 1: NP_523565.2
• Gene: spel1 / 34842
• FlyBaseID: FBgn0015546
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_194284.2
• Gene: MSH3 / 828659
• AraportID: AT4G25540
• Length: 1081
• Species: Arabidopsis thaliana
• Alignment Length: 962
• Identity: 250/962 - (25%)
• Similarity: 408/962 - (42%)
• Gaps: 173/962 - (17%)

  Fly    17 DTNARRNFIKFH---AKLGEKPATTVRFFDHTDRYTVHGSDDCELVAKIVYKSTAFIGALLPDDK 78
            :|::.|.:....   .:|..|....|...:...||...| :|.|:.|::       :|.....|.
plant    97 ETSSSRKYTPLEQQVVELKSKYPDVVLMVEVGYRYRFFG-EDAEIAARV-------LGIYAHMDH 153

  Fly    79 KETLQFVSMSKGNFELAVRELLLVR-NYRVEVYVKNSSDWEIE----------YRG-----SPGN 127
                .|::.|...|.|......||. .|::.| ||.:....|:          :||     :...
plant   154 ----NFMTASVPTFRLNFHVRRLVNAGYKIGV-VKQTETAAIKSHGANRTGPFFRGLSALYTKAT 213

  Fly   128 LLQFEDI---------LFSNKEVLVGNSIISLLVKLDGGG-------QRRVGVASVEQNDCKFQL 176
            |...|||         ..|....||  .::...||.:..|       ..||||..||.:..:...
plant   214 LEAAEDISGGCGGEEGFGSQSNFLV--CVVDERVKSETLGCGIEMSFDVRVGVVGVEISTGEVVY 276

  Fly   177 LEFLDDDFFTELEATVVLLGPKECLLP---SIEGEYSAVKTLLDRNGVMI---TMPKKSGDNDLL 235
            .||.|:...:.|||.::.|.|.|.||.   |.:.|...|......:.|.:   ::...|..|.:.
plant   277 EEFNDNFMRSGLEAVILSLSPAELLLGQPLSQQTEKFLVAHAGPTSNVRVERASLDCFSNGNAVD 341

  Fly   236 QDLNRLLRFAKGQQEDATGLKELQLQLASNALKTAIKYLDLVNDAGNLGHYEIKQLDLNRFVHL- 299
            :.::...:.:.|..||.   ||::|:.|...:...     .|:...|:.|..::.|.|. |.||
plant   342 EVISLCEKISAGNLEDD---KEMKLEAAEKGMSCL-----TVHTIMNMPHLTVQALALT-FCHLK 397

  Fly   300 ---------DSAAVAALNIMPKPGTHPSMPSYRWQ---------------SVLGVLDHCRTPQGH 340
                     ..|:..:|:    ..|..::.:...|               |:...::|..|..|.
plant   398 QFGFERILYQGASFRSLS----SNTEMTLSANTLQQLEVVKNNSDGSESGSLFHNMNHTLTVYGS 458

  Fly   341 RLMGQWVKQPLRSRNILNDRHNIVQ----CL--------------------LESPDTMETLS--L 379
            ||:..||..||..||:::.|.:.|.    |:                    :.||:....||  |
plant   459 RLLRHWVTHPLCDRNLISARLDAVSEISACMGSHSSSQLSSELVEEGSERAIVSPEFYLVLSSVL 523

  Fly   380 DYLKRIPDILMLTKKLMRRKANLQDLFRIYQVILRTPKILKVLHELDNSTIESVICAPFKSFLKD 444
            ..:.|..||.....::..|.|...:...:.:.||...|.::.|....:|.:.|:..|..:|.|
plant   524 TAMSRSSDIQRGITRIFHRTAKATEFIAVMEAILLAGKQIQRLGIKQDSEMRSMQSATVRSTL-- 586

  Fly   445 LTGLKQMVEQV---------------VDFEAIERGEYL--VKASFDS--RLMELQQMMTELYSKM 490
               |::::..:               ::.||..||:.|  :..|.|.  .|.|.:|.:..:..|:
plant   587 ---LRKLISVISSPVVVDNAGKLLSALNKEAAVRGDLLDILITSSDQFPELAEARQAVLVIREKL 648

  Fly   491 EELQFKCSQELNLDGKNQVKLESVAKLGHHFRITVKDDSVLRKNKNYRIVDVIKGGVRFTSDKLE 555
            :.......::|.:   ..::...|:.:.|...:.|  ||  :...|:..|:..|..:|:...::.
plant   649 DSSIASFRKKLAI---RNLEFLQVSGITHLIELPV--DS--KVPMNWVKVNSTKKTIRYHPPEIV 706

  Fly   556 GYADEFASCRTRYEEQQLSIV-----EEIIHVAVGYAAPLTLLNNELAQLDCLVSFAIAARSAPT 615
            ...||.|     ...:.|:||     :..:.....|..........||.||||.|.:..:|:  .
plant   707 AGLDELA-----LATEHLAIVNRASWDSFLKSFSRYYTDFKAAVQALAALDCLHSLSTLSRN--K 764

  Fly   616 PYVRPKMLEE-GARELVLEDVRHPCLELQEHVNFIANSVDFKKEECNMFIITGPNMGGKSTYIRS 679
            .||||:.::: ...|:.::..|||.||.....||:.|......|.....|||||||||||.|||.
plant   765 NYVRPEFVDDCEPVEINIQSGRHPVLETILQDNFVPNDTILHAEGEYCQIITGPNMGGKSCYIRQ 829

  Fly   680 VGTAVLMAHIGAFVPCSLATISMVDSILGRVGASDNIIKGLSTFMVEMIETSGIIRTATDKSLVI 744
            |....:||.:|:|||.|.|.:.::|.:..|:||||:|..|.|||:.|:.|.|.||||.:.:||||
plant   830 VALISIMAQVGSFVPASFAKLHVLDGVFTRMGASDSIQHGRSTFLEELSEASHIIRTCSSRSLVI 894

  Fly   745 IDELGRGTSTYEGCGIAWSIAEHLAKETKCFTLFATHFHEITKLAETL-STVKNCHMAAVA---- 804
            :|||||||||::|..||::..:||..|.:|..||.||:.||.:::... .:|...|::.:.
plant   895 LDELGRGTSTHDGVAIAYATLQHLLAEKRCLVLFVTHYPEIAEISNGFPGSVGTYHVSYLTLQKD 959

  Fly   805 ----DADDFTLLYQVRSGVMEKSFGIQVARLANFPEHVVQNAQEVYNEFEDE 852
                |.||.|.||::..|:..:|||.:||:||..|...::.|..:..:.|.|
plant   960 KGSYDHDDVTYLYKLVRGLCSRSFGFKVAQLAQIPPSCIRRAISMAAKLEAE 1011

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spel1	NP_523565.2	MutS_I	24..132	CDD:426350	25/126 (20%)
		MutS	174..890	CDD:440019	208/770 (27%)
MSH3	NP_194284.2	MutS	99..1011	CDD:440019	248/958 (26%)