Protein Alignment spel1 and MSH1

DIOPT Version :10

• Sequence 1: NP_523565.2
• Gene: spel1 / 34842
• FlyBaseID: FBgn0015546
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_189075.2
• Gene: MSH1 / 822021
• AraportID: AT3G24320
• Length: 1118
• Species: Arabidopsis thaliana
• Alignment Length: 842
• Identity: 184/842 - (21%)
• Similarity: 332/842 - (39%)
• Gaps: 188/842 - (22%)

  Fly   162 VGVASVEQNDCKFQLLEFLD----DDFFTELEATVVLLGPKECLLPSIEGEYSAVKTLLDRNGVM 222
            ||::...:..|...:.|.:.    ||..|| ||.|..|..:.|       .:..:...|..|...
plant   249 VGISRSARGYCMISIFETMKAYSLDDGLTE-EALVTKLRTRRC-------HHLFLHASLRHNASG 305

  Fly   223 ITMPKKSGDNDLL--QDLNRLLRFAKGQQEDATGLKELQLQLASNALKTAIKYLDLVNDAGNLGH 285
            .....:.|:..||  :..:|...:.:|..     |.|         |.:.:|.:..::|..:..:
plant   306 TCRWGEFGEGGLLWGECSSRNFEWFEGDT-----LSE---------LLSRVKDVYGLDDEVSFRN 356

  Fly   286 YEIKQLDLNRFVHLDSAAVAALNIMPK-----------PGTHPSMPSYRWQSVLGVLDHCRTPQG 339
            ..:...:..|.:||.:|  ..:..:|.           |.|...:||      |.|.|....|..
plant   357 VNVPSKNRPRPLHLGTA--TQIGALPTEGIPCLLKVLLPSTCSGLPS------LYVRDLLLNPPA 413

  Fly   340 HRLMGQWVKQPLRSRNILNDRHNIVQCLLESPDTMETLSLDYLKRIPDI-----LMLTKKLMRRK 399
                                 ::|...:.|:...|.|::..    ||:.     ..|.|.|.:|:
plant   414 ---------------------YDIALKIQETCKLMSTVTCS----IPEFTCVSSAKLVKLLEQRE 453

  Fly   400 ANLQDLFRIYQVI---------LRTPKILKVLHELDNSTIESVICAPFKSFLKDLTGLKQMVEQV 455
            ||..:..||..|:         ....:|||:|  :|.:.:.:.:...|.:|:.:.......:.::
plant   454 ANYIEFCRIKNVLDDVLHMHRHAELVEILKLL--MDPTWVATGLKIDFDTFVNECHWASDTIGEM 516

  Fly   456 VDFEAIERGE-------------YLVKASFDSRL--MELQQMMTELYSKMEELQFKCSQEL---- 501
            :..:..|..:             |.:::|:..|:  :.:::.:|::....|.|....:::.
plant   517 ISLDENESHQNVSKCDNVPNEFFYDMESSWRGRVKGIHIEEEITQVEKSAEALSLAVAEDFHPII 581

  Fly   502 --------NLDG-KNQV----KLESVAKLGHHFRI-----TVKDDSVLR-----KNKNYRIVDVI 543
                    :|.| |.::    :.|||...|..|..     |..:|.:.:     .:|..::
plant   582 SRIKATTASLGGPKGEIAYAREHESVWFKGKRFTPSIWAGTAGEDQIKQLKPALDSKGKKV---- 642

  Fly   544 KGGVRFTSDKLE------GYADEFASCRTRYEEQQLSI-VEEIIHVAVGYAAPLTLLNNELAQLD 601
             |...||:.|:|      ..|.|.|..|.....::||: ::..|:|.| :|:.|.:::..|....
plant   643 -GEEWFTTPKVEIALVRYHEASENAKARVLELLRELSVKLQTKINVLV-FASMLLVISKALFSHA 705

  Fly   602 C-----------LVSFAIAARSAPTPYVRPKMLEEGARELVLEDVRHPCLELQEHVNFIANSVDF 655
            |           ||.|::...:.|.         :||..:.|..:.....::... ..:.|:||.
plant   706 CEGRRRKWVFPTLVGFSLDEGAKPL---------DGASRMKLTGLSPYWFDVSSG-TAVHNTVDM 760

  Fly   656 KKEECNMFIITGPNMGGKSTYIRSVGTAVLMAHIGAFVPCSLATISMVDSILGRVGASDNIIKGL 720
            :    ::|::||||.||||:.:||:..|.|:...|..||...|.|...|||:..:.:.|:.:.|.
plant   761 Q----SLFLLTGPNGGGKSSLLRSICAAALLGISGLMVPAESACIPHFDSIMLHMKSYDSPVDGK 821

  Fly   721 STFMVEMIETSGIIRTATDKSLVIIDELGRGTSTYEGCGIAWSIAEHLAKETKCFTLFATHFHEI 785
            |:|.|||.|...|:..||.:|||:|||:.|||.|.:|..||.|:.|.| ..:.|..:.:||.|.|
plant   822 SSFQVEMSEIRSIVSQATSRSLVLIDEICRGTETAKGTCIAGSVVESL-DTSGCLGIVSTHLHGI 885

  Fly   786 TKLAETLSTVKNCHMAAVADADDFTLLYQVRSGVMEKSFGIQVARLANFPEHVVQNAQEVYNEFE 850
            ..|..|...:....|.|..........:::..||..:|...:.|:....||.|:|.|:.:|
plant   886 FSLPLTAKNITYKAMGAENVEGQTKPTWKLTDGVCRESLAFETAKREGVPESVIQRAEALY---- 946

  Fly   851 DEHVDKQKKEDKALLEKIQVAIQQLSTAGNNVDINVEDLTQLVTQFTKDIEQLDSDYFKSVL 912
               :....|:..|.:    |...|:.|:.||        .|.:.:.......|:.|..|:::
plant   947 ---LSVYAKDASAEV----VKPDQIITSSNN--------DQQIQKPVSSERSLEKDLAKAIV 993

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spel1	NP_523565.2	MutS_I	24..132	CDD:426350
		MutS	174..890	CDD:440019	177/806 (22%)
MSH1	NP_189075.2	MutS_I	126..226	CDD:426350
		ABC_MutS_homologs	748..934	CDD:213210	64/191 (34%)
		GIY-YIG_MSH	1025..1094	CDD:198385