DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rab14 and RAB12

DIOPT Version :9

Sequence 1:	NP_788056.1	Gene:	Rab14 / 34840	FlyBaseID:	FBgn0015791	Length:	239	Species:	Drosophila melanogaster
Sequence 2:	NP_001020471.3	Gene:	RAB12 / 201475	HGNCID:	31332	Length:	340	Species:	Homo sapiens

Alignment Length:	196	Identity:	77/196 - (39%)
Similarity:	118/196 - (60%)	Gaps:	3/196 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PYNYNYIFKYIIIGDMGVGKSCLLHQFTEKKFMANCPHTIGVEFGTRIIEVDDKKIKLQIWDTAG 93
            |...::..:.||||..||||:.|:.:||:..|...|..|:||:|..:.:|:..|||:||||||||
Human   132 PRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAG 196

  Fly    94 QERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIFLIGNKSDLESTREV 158
            ||||.::|.:|||.|.|.::|||||::.|::.|..|:.......:....:.|:|||.|.|:.||:
Human   197 QERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREI 261

  Fly   159 TYEEAKEFADE-NGLMFLEASAMTGQNVEEAFLETARKIYQNIQEG--RLDLNASESGVQHRPSQ 220
            |.::.::||.: .|:.|.||||....||:|.||:....|.:.:...  |.:|:.|...:|..|..
Human   262 TRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPLDILRNELSNSILSLQPEPEI 326

  Fly   221 P 221
            |
Human   327 P 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab14	NP_788056.1	Rab14	34..199	CDD:133322	70/165 (42%)
RAB12	NP_001020471.3	Rab12	139..340	CDD:206699	76/189 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910