DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab14 and Rab5b

DIOPT Version :9

Sequence 1:	NP_788056.1	Gene:	Rab14 / 34840	FlyBaseID:	FBgn0015791	Length:	239	Species:	Drosophila melanogaster
Sequence 2:	NP_803130.1	Gene:	Rab5b / 19344	MGIID:	105938	Length:	215	Species:	Mus musculus

Alignment Length:	194	Identity:	77/194 - (39%)
Similarity:	118/194 - (60%)	Gaps:	1/194 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 FKYIIIGDMGVGKSCLLHQFTEKKFMANCPHTIGVEFGTRIIEVDDKKIKLQIWDTAGQERFRAV 100
            ||.:::|:..||||.|:.:|.:.:|......|||..|.|:.:.:||..:|.:|||||||||:.::
Mouse    21 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSL 85

  Fly   101 TRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIFLIGNKSDLESTREVTYEEAKE 165
            ...|||||..|::|||||.:.|:....:|:.:.:...:||.||.|.|||:||.:.|.|.||||:.
Mouse    86 APMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQA 150

  Fly   166 FADENGLMFLEASAMTGQNVEEAFLETARKIYQNIQEGRLDLNASESGVQ-HRPSQPSRTSLSS 228
            :||:|.|:|:|.||.|..||.:.||..|:|:.::..:..........||. |..||.:::...|
Mouse   151 YADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSRGVDLHEQSQQNKSQCCS 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab14	NP_788056.1	Rab14	34..199	CDD:133322	71/162 (44%)
Rab5b	NP_803130.1	Rab5_related	20..182	CDD:206653	71/160 (44%)
		Effector region. /evidence=ECO:0000255	49..57		3/7 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	186..215		6/29 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910