DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab14 and dnajc27

DIOPT Version :9

Sequence 1:	NP_788056.1	Gene:	Rab14 / 34840	FlyBaseID:	FBgn0015791	Length:	239	Species:	Drosophila melanogaster
Sequence 2:	NP_001096154.1	Gene:	dnajc27 / 100038110	XenbaseID:	XB-GENE-490420	Length:	1116	Species:	Xenopus tropicalis

Alignment Length:	316	Identity:	64/316 - (20%)
Similarity:	100/316 - (31%)	Gaps:	108/316 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VVNKLHERIDYFIEKCPNMTAAPYNYNYIFKYIIIGD---------------------MGVGKSC 50
            ::|:|..|.|....|           |:..:..|:||                     ||:....
Frog   343 LLNELFARFDKLAAK-----------NHQLRIKILGDCYYCICGLPDYREDHAACSIMMGLAMVD 396

  Fly    51 LLHQFTEKKFMANCPHTIGVEFGTRIIEV-DDKKIKLQIWDTAGQERFRAVTRSYYRGAAGALMV 114
            .: .:..:|...:....:||..||.|..| ..|:.:..:|.|       .||.:....|.|....
Frog   397 AI-SYVREKTKTDVDMRVGVHSGTVIGGVLGQKRWQYDVWST-------DVTLANKMEAGGIPGR 453

  Fly   115 YDITRRSTYNHLSSWL--------TDTRNLTNPSTVIFLI-----------------------GN 148
            ..|: :|||:.|....        |....|.....|.:|:                       ||
Frog   454 VHIS-QSTYDCLKGEFEVEPGEGGTRCDYLREKGIVTYLVIVPKQPINKNGINGVKLSLTSSHGN 517

  Fly   149 KSDLESTRE---------VTYEEAKE---------FADENGLMFL----EASAMTGQN------- 184
            ...|.:|:|         .|.:|.:|         |.:....:.|    |......||
Frog   518 SPQLINTKECNGSIHTTCTTPDENEELDTRVVNPSFPNPRRRLRLRDLAERVIDAQQNEQELNKL 582

  Fly   185 VEEAFLETARKIYQNIQEGRLDLNASESGVQHRPSQPSRTSLSSE-ATGAKDQCSC 239
            :.||.||  |:..| :.:|:.....|...:  .|...:|.|:..| .:||...|||
Frog   583 LNEALLE--RETVQ-VLKGKYTYRLSMRFI--NPEMETRFSVEKEKQSGAAFSCSC 633

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab14	NP_788056.1	Rab14	34..199	CDD:133322	46/246 (19%)
dnajc27	NP_001096154.1	AC_N	<37..291	CDD:292831
		CYCc	273..469	CDD:214485	30/145 (21%)
		Guanylate_cyc	310..482	CDD:278633	31/158 (20%)
		CYCc	854..1073	CDD:214485
		Guanylate_cyc	885..1093	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910