DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mTTF and Mterf2

DIOPT Version :9

Sequence 1:	NP_609709.1	Gene:	mTTF / 34837	FlyBaseID:	FBgn0028530	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_030101190.1	Gene:	Mterf2 / 74238	MGIID:	1921488	Length:	402	Species:	Mus musculus

Alignment Length:	219	Identity:	47/219 - (21%)
Similarity:	80/219 - (36%)	Gaps:	50/219 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 LLEALRERFRFT--DAELQKI---ISDEL-VHRCYRGRSLTL--------VMDTLQLEGVSRRSF 125
            |:|...|.| ||  :.|.||:   ...|| :......|.||.        |.:..|:.||.:.|:
Mouse   149 LIEQFPESF-FTVKNQENQKLNVQFFQELGLRNVVISRFLTTASSIFHNPVENNKQMIGVLQESY 212

  Fly   126 VEYPWLLSLDNKRLELKMQLLKSMDFKDINHFVPFLRLTVPR----------------------L 168
                  |:|.......|:.|||.:...      ||:.|..||                      |
Mouse   213 ------LNLGGSEANAKVWLLKLLSQN------PFIVLHSPRAVGETLKCLQGQGFTDSEVLQLL 265

  Fly   169 RKLVGALNSERDAMPQRNRVYYISEKLDVSPDIVSKYLSKRLFILEMPFEMFEKNLQHMIDYNVS 233
            .||.|.|...:....| |.:.:.....:.:...:.:.:.|...:|..|..:.|:.:|.::...:|
Mouse   266 SKLKGFLFQLQPGSIQ-NSISFTKTTFECTDYDLRQLVVKCPALLCYPASVLEERIQALLKEGIS 329

  Fly   234 PINVLKDLWAFRYTPKSVQLRLER 257
            ...:.:.......||:.:|.|:.:
Mouse   330 IAQIRESPMVLELTPQIIQYRIRK 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mTTF	NP_609709.1	mTERF	<284..378	CDD:327630
Mterf2	XP_030101190.1	mTERF	75..377	CDD:388635	47/219 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838205
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15437
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030