Protein Alignment mTTF and MTERF3

DIOPT Version :9

• Sequence 1: NP_609709.1
• Gene: mTTF / 34837
• FlyBaseID: FBgn0028530
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_057026.3
• Gene: MTERF3 / 51001
• HGNCID: 24258
• Length: 417
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 95/449 - (21%)
• Similarity: 165/449 - (36%)
• Gaps: 124/449 - (27%)

  Fly     2 IRSLLRSFETALK--------LHAGLNMHPM----HCSRRLLFSQYENRA--SPSRLTSSGTLGS 52
            :|||:.:.:...:        || |.:..|.    :|..:..|..|...:  :.|:.|||.:..:
Human    17 LRSLINAAQLTKRFTRPARTLLH-GFSAQPQISSDNCFLQWGFKTYRTSSLWNSSQSTSSSSQEN 80

  Fly    53 NEAENDYVPYRQDRETGTK------TRVLLEALRE------RFRFTDAELQKIISD------ELV 99
            |.|::..:|...::...|:      :.:.||.|.|      ....::.|..:||:|      ...
Human    81 NSAQSSLLPSMNEQSQKTQNISSFDSELFLEELDELPPLSPMQPISEEEAIQIIADPPLPPASFT 145

  Fly   100 HRCYRGRSLTLVMDTLQLEGVSRRSFVEYPWLLSLDNKRLELKMQLLKSMDF-KDINHFVPFLRL 163
            .|.|...|.||  ..|.|.||......::|...:           ||..:|| |||...:.||
Human   146 LRDYVDHSETL--QKLVLLGVDLSKIEKHPEAAN-----------LLLRLDFEKDIKQMLLFL-- 195

  Fly   164 TVPRLRKLVGALNSERDAMPQRN-------------RVYYISEKLDVSPDIVSKYLSKRLFILEM 215
                  |.||..:::..|...:|             ||.|:..| :.|...|::.:.|..|:|..
Human   196 ------KDVGIEDNQLGAFLTKNHAIFSEDLENLKTRVAYLHSK-NFSKADVAQMVRKAPFLLNF 253

  Fly   216 PFEMFEKNLQHMIDYNVSPINVLKDLWAFRYTPKSVQLRLERAKRAKKDKIMPWMVRCPEPILQR 280
            ..|..:..|...                        |..||.:.:..:|.:    ||.|. :|..
Human   254 SVERLDNRLGFF------------------------QKELELSVKKTRDLV----VRLPR-LLTG 289

  Fly   281 SLKLSLDELKVLGEFSSVVEYLAHR--LGFSTSEAKAIMDKHPQVHTVRVTKIKEVLDYLLDEAQ 343
            ||:...:.:||            :|  |||..:|.:.::.:.|::.|....|:.|..|::.:...
Human   290 SLEPVKENMKV------------YRLELGFKHNEIQHMITRIPKMLTANKMKLTETFDFVHNVMS 342

  Fly   344 FTRFEVAQNPRILCHSLKTTKERMEELKSHGCRPSSLVILCRSRREYDKFLQNWISHER 402
            .....:.:.|::....|...|||            .|.:....|.:||....|:||.::
Human   343 IPHHIIVKFPQVFNTRLFKVKER------------HLFLTYLGRAQYDPAKPNYISLDK 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mTTF	NP_609709.1	mTERF	<284..378	CDD:327630	17/95 (18%)
MTERF3	NP_057026.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..96		7/26 (27%)
		mTERF	<159..398	CDD:327630	64/304 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	1	0.960