DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Send2 and Prss36

DIOPT Version :9

Sequence 1:	NP_609708.2	Gene:	Send2 / 34836	FlyBaseID:	FBgn0264253	Length:	239	Species:	Drosophila melanogaster
Sequence 2:	XP_017167884.1	Gene:	Prss36 / 77613	MGIID:	1924863	Length:	863	Species:	Mus musculus

Alignment Length:	263	Identity:	73/263 - (27%)
Similarity:	109/263 - (41%)	Gaps:	79/263 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PEERIIGGQPIGIEEAPWQVSIQRDGKHLCGGSIYSADIIITAAHC------------------V 69
            |..||:||........|||||:.:.|.|:||||:.:...:::||||                  |
Mouse    44 PSSRIVGGSDAHPGTWPWQVSLHQGGGHICGGSLIAPSWVLSAAHCFVTNGTLEPADELSVLLGV 108

  Fly    70 QGQ-----GYQVRA-GSALKNSNGSVVDVAAIRTHEGLGNDIAIVRLSKPLEFTNQVQPIPLAKT 128
            ..|     |..:|: .:.|...|.|.|:         ||.|:|::||:.|.:....|:|:.|.:.
Mouse   109 HSQDGPLEGAHMRSVATILIPDNYSTVE---------LGADLALLRLASPAKLGPSVRPVCLPRA 164

  Fly   129 NP--PPGSIAFVSGWGSSSYYSHPIDLQ-GVNLYIQW---------------------PYYCGLT 169
            :.  ..|:..:.:|||         |:| .|.|.:.|                     |....||
Mouse   165 SHLFAHGTACWATGWG---------DVQEAVPLPLPWVLQEVELRLLGEAACQCLYSRPGPFNLT 220

  Fly   170 ---EPSRICAG--SFGRAACKGDSGGPLVFDQQ----LVGVVSGGTKDC---TYSSIYTSVPYFR 222
               .|..:|||  :..|..|:||||||||.:..    |.|:.|.|. .|   ....::|:|..:.
Mouse   221 FQLLPGMLCAGYPAGRRDTCQGDSGGPLVCEDGGRWFLAGITSFGF-GCGRRNRPGVFTAVAPYE 284

  Fly   223 EWI 225
            .||
Mouse   285 SWI 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Send2	NP_609708.2	Tryp_SPc	26..225	CDD:214473	70/258 (27%)
Send2	NP_609708.2	Tryp_SPc	27..225	CDD:238113	69/257 (27%)
Prss36	XP_017167884.1	Tryp_SPc	48..290	CDD:238113	71/259 (27%)
		Tryp_SPc	331..532	CDD:389826
		Tryp_SPc	607..789	CDD:389826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100