DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Send2 and Prss36

DIOPT Version :9

Sequence 1:	NP_609708.2	Gene:	Send2 / 34836	FlyBaseID:	FBgn0264253	Length:	239	Species:	Drosophila melanogaster
Sequence 2:	XP_038942639.1	Gene:	Prss36 / 497040	RGDID:	1593186	Length:	874	Species:	Rattus norvegicus

Alignment Length:	247	Identity:	73/247 - (29%)
Similarity:	109/247 - (44%)	Gaps:	47/247 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PEERIIGGQPIGIEEAPWQVSIQRDGKHLCGGSIYSADIIITAAHCVQGQG-------YQVRAGS 80
            |..||:||........|||||:...|.|:||||:.:...:::||||....|       :.|..|
  Rat    55 PSSRIVGGSDAHPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFVTNGTLEPADEWSVLLG- 118

  Fly    81 ALKNSNGSVV-----DVAAIRTHEG-----LGNDIAIVRLSKPLEFTNQVQPIPLAKTNP--PPG 133
             :.:.:|.:.     .||.|...:.     ||.|:|::||:.|.:....|:|:.|.:.:.  ..|
  Rat   119 -VHSQDGPLEGAHMRSVATILVPDNYSRVELGADLALLRLASPAKLGPSVKPVCLPRASHLFAHG 182

  Fly   134 SIAFVSGWG---SSSYYSHPIDLQGVNLYIQWPYYC----------GLT---EPSRICAG--SFG 180
            :..:.:|||   .|.....|..||.|.|.:.....|          .||   .|..:|||  ...
  Rat   183 TACWATGWGDVQESDPLPVPWVLQEVELKLLGETACQCLYSRPGPFNLTLQLLPGMLCAGYPEGR 247

  Fly   181 RAACKGDSGGPLVFDQQ----LVGVVSGGTKDC---TYSSIYTSVPYFREWI 225
            |..|:||||||||.:..    |.|:.|.|. .|   ....::|:|.::..||
  Rat   248 RDTCQGDSGGPLVCEDGGRWFLAGITSFGF-GCGRRNRPGVFTAVAHYESWI 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Send2	NP_609708.2	Tryp_SPc	26..225	CDD:214473	70/242 (29%)
Send2	NP_609708.2	Tryp_SPc	27..225	CDD:238113	69/241 (29%)
Prss36	XP_038942639.1	Tryp_SPc	59..301	CDD:238113	71/243 (29%)
		Tryp_SPc	338..532	CDD:419748
		Tryp_SPc	607..802	CDD:419748
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100