DRSC/TRiP Functional Genomics Resources

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Protein Alignment Send2 and KLK2

DIOPT Version :9

Sequence 1:NP_609708.2 Gene:Send2 / 34836 FlyBaseID:FBgn0264253 Length:239 Species:Drosophila melanogaster
Sequence 2:NP_005542.1 Gene:KLK2 / 3817 HGNCID:6363 Length:261 Species:Homo sapiens


Alignment Length:253 Identity:74/253 - (29%)
Similarity:121/253 - (47%) Gaps:30/253 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 LLLLALNSLSAGPVIRPEERIIGGQPIGIEEAPWQVSIQRDGKHLCGGSIYSADIIITAAHCV-- 69
            :|.:||:....|.|...:.||:||........||||::...|...|||.:.....::|||||:  
Human     5 VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK 69

  Fly    70 --------------QGQGYQVRAGSALKNS--NGSVVDVAAIRTHEGLGNDIAIVRLSKPLEFTN 118
                          :..|.:|....:..:.  |.|::...::|..|...:|:.::|||:|.:.|:
Human    70 NSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITD 134

  Fly   119 QVQPIPLAKTNPPPGSIAFVSGWGS--SSYYSHPIDLQGVNLYIQWPYYCGLTEPSRI-----CA 176
            .|:.:.|....|..|:..:.|||||  ...:..|..||.|:|::.....|......::     ||
Human   135 VVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCA 199

  Fly   177 GSF--GRAACKGDSGGPLVFDQQLVGVVSGGTKDCTY---SSIYTSVPYFREWILNAI 229
            |.:  |:..|.||||||||.:..|.|:.|.|.:.|..   .::||.|.::|:||.:.|
Human   200 GLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Send2NP_609708.2 Tryp_SPc 26..225 CDD:214473 66/228 (29%)
Tryp_SPc 27..225 CDD:238113 65/227 (29%)
KLK2NP_005542.1 Tryp_SPc 25..256 CDD:238113 67/230 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165147430
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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