Protein Alignment Send2 and KLK1

DIOPT Version :9

• Sequence 1: NP_609708.2
• Gene: Send2 / 34836
• FlyBaseID: FBgn0264253
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 78/263 - (29%)
• Similarity: 112/263 - (42%)
• Gaps: 35/263 - (13%)

  Fly     1 MFIQSFLLLLALNSLSAGPVIRPEERIIGGQPIGIEEAPWQVSIQRDGKHLCGGSIYSADIIITA 65
            |:.....|.|:|....|.|.|  :.||:||........|||.::.......|||.:.....::||
Human     1 MWFLVLCLALSLGGTGAAPPI--QSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTA 63

  Fly    66 AHCVQGQGYQVRAG--SALKNSN-GSVVDVAAIRTHEGL----------------GNDIAIVRLS 111
            |||: ...||:..|  :...:.| ...|.|:....|.|.                .:|:.::||:
Human    64 AHCI-SDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLT 127

  Fly   112 KPLE-FTNQVQPIPLAKTNPPPGSIAFVSGWGS--SSYYSHPIDLQGVNLYIQWPYYCGLTEPSR 173
            :|.: .|:.|:.:.|....|..||....|||||  ...:|.|.|||.|:|.|.....|......:
Human   128 EPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQK 192

  Fly   174 I-----CAGSF--GRAACKGDSGGPLVFDQQLVGVVSGGTKDC---TYSSIYTSVPYFREWILNA 228
            :     |.|..  |:..|.|||||||:.|..|.||.|.|...|   ...|:...|..:.:||.:.
Human   193 VTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDT 257

  Fly   229 IDE 231
            |.|
Human   258 IAE 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Send2	NP_609708.2	Tryp_SPc	26..225	CDD:214473	67/230 (29%)
		Tryp_SPc	27..225	CDD:238113	66/229 (29%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	68/232 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147432
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840