DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Send2 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_609708.2	Gene:	Send2 / 34836	FlyBaseID:	FBgn0264253	Length:	239	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	85/250 - (34%)
Similarity:	118/250 - (47%)	Gaps:	37/250 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLALNSLSAGPVIRPEERIIGGQPIGIEEAPWQVSIQRDGKHLCGGSIYSADIIITAAHC----V 69
            |::|..|..|..:: ..|::||.....:..|||||||.:.:|:|||||.....|:|||||    :
  Rat   229 LVSLRCLDCGKSLK-TTRVVGGVEASADSWPWQVSIQYNKQHVCGGSILDHHWILTAAHCFRKYL 292

  Fly    70 QGQGYQVRAGSALKNSNGSVVDVAAIRTHE-----GLGNDIAIVRLSKPLEFTNQVQPI--PLAK 127
            ....::|||||. |..|...:.||.|...|     ....|||:|:|..||.|:..|:||  |.:.
  Rat   293 DVSSWKVRAGSN-KLGNSPSLPVAKIFIAEPNPLQPKEKDIALVKLKMPLTFSGSVRPICLPFSD 356

  Fly   128 TNPPPGSIAFVSGWGSSSYYS------------HPIDLQGVNLYIQWPYYCGLTEPSRICAGS-- 178
            ....|....:|.|||.:....            ..||....|..   ..|.|......:|||:
  Rat   357 EELIPTMPVWVIGWGFTEENGGKMSDTLLQASVQVIDSARCNAE---DAYQGEVTAGMLCAGTPQ 418

  Fly   179 FGRAACKGDSGGPLVFDQ---QLVGVVSGGTKDCTYSS---IYTSVPYFREWILN 227
            .|:..|:|||||||::..   |:||:||.| ..|...|   :||.|..:.:||.|
  Rat   419 GGKDTCQGDSGGPLMYHYDKWQVVGIVSWG-YGCGSPSTPGVYTKVTAYLDWIYN 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Send2	NP_609708.2	Tryp_SPc	26..225	CDD:214473	78/229 (34%)
Send2	NP_609708.2	Tryp_SPc	27..225	CDD:238113	77/228 (34%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346	3/8 (38%)
		Tryp_SPc	245..470	CDD:214473	78/229 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341104
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840