DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Send2 and Prss53

DIOPT Version :9

Sequence 1:	NP_609708.2	Gene:	Send2 / 34836	FlyBaseID:	FBgn0264253	Length:	239	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	245	Identity:	64/245 - (26%)
Similarity:	106/245 - (43%)	Gaps:	43/245 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LALNSL-SAGPVIRPEERIIGGQPIGIEEAPWQVSIQRDGKHLCGGSIYSADIIITAAHCVQG-- 71
            :|..|| ||||           |...:.:.||...::..||..|||::.|..:::|||||..|
Mouse   294 VACGSLRSAGP-----------QAGALSQWPWDARLKHHGKLACGGALVSEVVVLTAAHCFIGRQ 347

  Fly    72 --QGYQVRAGSALKNSNGSVVDVAAIRTHEGLGNDIAIVRLSKPLEFTNQVQP--IPLAKTNPPP 132
              :.:.|..|:..:......:.:....||...|.|:|.:.|::|:.....::|  :|.|..:.|.
Mouse   348 TLEEWSVGLGAGPEEWGLKQLILHGAYTHPEGGYDVAFLLLAQPVTLGPGLRPLCLPYADHHLPD 412

  Fly   133 GSIAFVSGWGSSSYYSHPIDLQGVNLYIQWPYYCGLTE-----------PSRICAGSFGRAA-CK 185
            |...:|.|....:..::|   |.|.:.:..|..|....           |..:|....|... |:
Mouse   413 GEHGWVLGLTQKAGINYP---QTVPVTVLGPMACSRQHAAPGGTGIPILPGMVCTTVVGEPPHCE 474

  Fly   186 GDSGGPLVFDQQ----LVGVVSGGTKDCTYSS----IYTSVPYFREWILN 227
            |.||.|||.:.:    |||:.|.|  |...||    ::.::..:.:||.|
Mouse   475 GLSGAPLVHEIRGTWFLVGLHSFG--DTCQSSAKPAVFAALSAYEDWISN 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Send2	NP_609708.2	Tryp_SPc	26..225	CDD:214473	54/224 (24%)
Send2	NP_609708.2	Tryp_SPc	27..225	CDD:238113	54/223 (24%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46
		Tryp_SPc	45..271	CDD:238113
		Tryp_SPc	311..522	CDD:238113	55/215 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100