Protein Alignment Send2 and GZMH

DIOPT Version :9

• Sequence 1: NP_609708.2
• Gene: Send2 / 34836
• FlyBaseID: FBgn0264253
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_219491.1
• Gene: GZMH / 2999
• HGNCID: 4710
• Length: 246
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 78/250 - (31%)
• Similarity: 111/250 - (44%)
• Gaps: 38/250 - (15%)

  Fly     3 IQSFLLLLA-LNSLSAGPVIRPEERIIGGQPIGIEEAPWQVSI---QRDGKHLCGGSIYSADIII 63
            :|.|||||| |.:..||     .|.||||........|:...:   |...:..|||.:...|.::
Human     1 MQPFLLLLAFLLTPGAG-----TEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVL 60

  Fly    64 TAAHCVQGQGYQVRAGS-ALKNSNGSVVDVAAIR-------THEGLGNDIAIVRLSKPLEFTNQV 120
            ||||| ||....|..|: .:|....:...:...|       ..:...|||.:::|.:..::|..|
Human    61 TAAHC-QGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKWTTAV 124

  Fly   121 QP--IPLAKTNPPPGSIAFVSGWGSSSYYSHPIDLQGVNLYIQWPYYCGLTEPSRICAGSFGRAA 183
            :|  :|.:|....||.:..|:|||..|..:....||.|.|.:|....|     .|:..|::.||.
Human   125 RPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQC-----ERLFHGNYSRAT 184

  Fly   184 --C-----------KGDSGGPLVFDQQLVGVVSGGTKDCTYSSIYTSVPYFREWI 225
              |           |||||||||......|::|.|.|..|...:|..|.:|..||
Human   185 EICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWI 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Send2	NP_609708.2	Tryp_SPc	26..225	CDD:214473	65/224 (29%)
		Tryp_SPc	27..225	CDD:238113	65/223 (29%)
GZMH	NP_219491.1	Tryp_SPc	21..242	CDD:238113	66/224 (29%)
		Mediates the preference for acidic residues at the P3' and P4' sites	46..48		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1076876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920