Protein Alignment Send2 and KLK8

DIOPT Version :10

• Sequence 1: NP_609708.2
• Gene: Send2 / 34836
• FlyBaseID: FBgn0264253
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 73/237 - (30%)
• Similarity: 117/237 - (49%)
• Gaps: 25/237 - (10%)

  Fly    16 SAGPVIRPEERIIGGQPIGIEEAPWQVSIQRDGKHLCGGSIYSADIIITAAHCVQGQGYQVRAGS 80
            :||.....|::::||........|||.::.:..:.||||.:...:.::|||||.:.: |.||.|.
Human    67 AAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPK-YTVRLGD 130

  Fly    81 -ALKNSNGSVVDVAAIRT--H--------EGLGNDIAIVRLSKPLEFTNQVQPIPLAKTNPPPGS 134
             :|:|.:|...::..:::  |        |...:|:.:::|.......::|:||.||.....||.
Human   131 HSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQ 195

  Fly   135 IAFVSGWG--SSSYYSHPIDLQGVNLYIQWPY------YCGLTEPSRICAGSF-GRAACKGDSGG 190
            ...|||||  :|...:.|..|....:.| :|.      |.|......:||||. |...|:|||||
Human   196 KCTVSGWGTVTSPRENFPDTLNCAEVKI-FPQKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGG 259

  Fly   191 PLVFDQQLVGVVSGGTKDCTYS---SIYTSVPYFREWILNAI 229
            |||.|..|.|:.|.|:..|..|   .:||::..:.:||...|
Human   260 PLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Send2	NP_609708.2	Tryp_SPc	26..225	CDD:214473	67/221 (30%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	67/221 (30%)