DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33090 and AT1G33700

DIOPT Version :9

Sequence 1:	NP_788055.2	Gene:	CG33090 / 34835	FlyBaseID:	FBgn0028916	Length:	948	Species:	Drosophila melanogaster
Sequence 2:	NP_001031135.1	Gene:	AT1G33700 / 840261	AraportID:	AT1G33700	Length:	947	Species:	Arabidopsis thaliana

Alignment Length:	997	Identity:	315/997 - (31%)
Similarity:	480/997 - (48%)	Gaps:	206/997 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 VPKYGLKLKFDHVWP----EKRIQN-------VRASIRQTLPMVPLVCRYAAYYWKVSRE----G 99
            ||:...|:..|...|    |:::.:       .:.|.|..:.:.||..|    .|:.:::    |
plant     4 VPEDQNKMVIDDKLPPFSWERKLNSQAKTPSEFKLSKRDHMHLFPLGYR----LWRHTKDEAAKG 64

  Fly   100 RRVYMDYYYMENGKQIYGVPIGGIGGGTIGRGYAGEFCRFQMRPGIYEYNVVLANQFIVTIKDPK 164
            |....|.:...:....:|||:||||.|:|||.|.|||.:|::.|.|.|...:|.|||...:..|.
plant    65 RASIFDIFRKHHITGDHGVPLGGIGSGSIGRSYKGEFQQFKLFPKICEEAPILTNQFSAFVSRPG 129

  Fly   165 G---CTIFQSLLSKCSTRDKTSDPDGDPDGERTKCQLPNCSSRAKQPLSAWHSNIEDTRCSYTGL 226
            |   .|:.      |.::.:....:|   |...:.|.||..      :.:|..|:...:.:|..|
plant   130 GVKHSTVL------CPSKPQVVKDNG---GYLCQGQAPNMG------IESWDWNMTGEKSTYHAL 179

  Fly   227 YPRSWTEYDLSHYG-----VRLTCRQVSPVIPHEYRESSLPCAVFVWSVENVCDQERKVSITFTF 286
            ||||||.||    |     :|:..|||||.|||.|.|||||.:||.::|.|...:...|::.||:
plant   180 YPRSWTVYD----GEPDPELRIVSRQVSPFIPHNYEESSLPVSVFNFTVTNTGAEPAIVTLLFTW 240

  Fly   287 KNGTG----------NKKQDAEGGAESQLISEGNAKGVSIRQKISEMPCSYNLACRVLPEISITR 341
            :|..|          |....|:.|..:..:....|.|        ..|.||.:|.:...::.::.
plant   241 ENSVGGASGLTGQHFNSTMKAKDGVHAVALQHKTANG--------HPPVSYAIAAKETEDVRVSS 297

  Fly   342 CPQFDPAG------NGEQLWAQLKEHG---QLSEHPTSEALKTKDIGVAVCGQVALKPMASHDLE 397
            ||.|..:|      ....:|.::|::.   :|:.:..|.:.....||.|:..:|.:.|.....:.
plant   298 CPCFIVSGTTPNQITAGDMWDEIKKNASFDKLTSNACSPSKPGTSIGAAIAAKVKVPPGCDRTVT 362

  Fly   398 FVLAWDMPKIQFPRKMQTHTRYYTKYFDDSGDSGPRICEYALRQYSTWERLIDAWQRPILNDETL 462
            |.|:||.|:.:|..|  |:.|.||:::...|::...:...||..:..||..|:.||.|:|.|.||
plant   363 FSLSWDCPEARFDEK--TYHRRYTRFYGSLGNAAVAMAHDALLNFPEWETQIEEWQAPVLADTTL 425

  Fly   463 PDWYKCAIFNQLYFISDGGTIW------------------------------------------- 484
            |:||:..:||:||:.:.|||:|
plant   426 PEWYRVTLFNELYYFNSGGTMWTDGLPPKQSLDSIGRRKISLGLSTIDKNDQDQNNVALDILGRI 490

  Fly   485 ----------LKCDSSLGKELAYDDPRLAYGRFGYLEGHEYRMYNTYDVHFYASPALAHLWPNLQ 539
                      |..:::||..:..:... ..|:|.||||.:|.||||||||||:|.||..|:|.::
plant   491 DAVCSQIHAPLTSNAALGNTMIQNTTE-NIGQFLYLEGVQYLMYNTYDVHFYSSFALLMLFPKIE 554

  Fly   540 VSLQYDFKDAIAAELNDTRKMLYDGKVMPRKVKNCVPHDLGDPDEEPFTLINCYNIHDVNDWKDL 604
            :|:|.||..|:....:..::::..|:.:.|||...||||:|..|  |:..:|.||:.:.:.||||
plant   555 LSIQRDFAAAVLMHDSSKKQVMSSGEFVTRKVLGAVPHDIGLND--PWFELNAYNLFNTDRWKDL 617

  Fly   605 NTKFVLQVYRDYYVLNELAQAQSDNASKFSSIEFIDKESLYELYSQDNKRKNSADEKQQNRKSAS 669
            |:|||||||||.....:|..|::...|.:::|.::|
plant   618 NSKFVLQVYRDVVATGDLNFAKAVWPSVYTAIAYLD----------------------------- 653

  Fly   670 MYINETNGKVYLMDAIGYLKAMYASCKAIMERTIEYDKDNDGLIENTKMPDQTYDSWVMDGPSAY 734
                                              ::|||.||:|||...||||||:|...|.|||
plant   654 ----------------------------------QFDKDGDGMIENEGFPDQTYDAWSCSGVSAY 684

  Fly   735 CSGLWLAALQAMSAMATILDQPNDCLRYQDILEKGKRSLEEKLWNGSYYRFDLSHS-HRDTIMAD 798
            |.|||:|||||.||:|..:......:.:....||. ||:.||||||||:.:|.|.| ...:|:||
plant   685 CGGLWVAALQAGSALAREIGDNGAAVYFNAKYEKA-RSVYEKLWNGSYFNYDNSRSGSSSSILAD 748

  Fly   799 QLCGHWYLKSCGFDYEIYPKENVRTALKRIYDNNVMGFHEGNIGAANGFIANASEPTKPGHVDNS 863
            |:.|.||.::||.. .|..:|.::.||:.:||.|||...:|..||.||.:.:       |.||.|
plant   749 QMAGQWYARACGLK-PIAKEEWIKKALETVYDFNVMRVRDGTRGAVNGMLPD-------GRVDTS 805

  Fly   864 NIQAEEVWPGVVYALAATMIQEGMFEEAFQTAGGMYKTL-SQR-IGMNFETPEALYGEKRYRSIG 926
            .:.:.|||.|..|::||.|||||:.::.|:||.|:|:.. |.| :|..|:||||......|||:.
plant   806 TMVSREVWAGTTYSVAACMIQEGLADKGFRTASGIYEAAWSDRGLGCAFQTPEAWTTNDEYRSLC 870

  Fly   927 YMRPLSIWSMQVALERRRAQRD 948
            |||||:||.:|.|....:..|:
plant   871 YMRPLAIWGIQWAHTMPKPNRE 892

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33090	NP_788055.2	GBA2_N	132..445	CDD:289023	94/339 (28%)
CG33090	NP_788055.2	DUF608	505..937	CDD:282531	168/434 (39%)
AT1G33700	NP_001031135.1	Glyco_hydr_116N	95..405	CDD:371967	95/338 (28%)
AT1G33700	NP_001031135.1	DUF608	520..880	CDD:368056	168/433 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	315	1.000	Domainoid score	I299
eggNOG	1	0.900	-	-		E1_COG4354
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	517	1.000	Inparanoid score	I295
OMA	1	1.010	-	-		QHG63864
OrthoDB	1	1.010	-	-		D207392at2759
OrthoFinder	1	1.000	-	-		FOG0003795
OrthoInspector	1	1.000	-	-		otm2806
orthoMCL	1	0.900	-	-		OOG6_105042
Panther	1	1.100	-	-	O	PTHR12654
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2650
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840