DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33090 and AT4G10060

DIOPT Version :9

Sequence 1:	NP_788055.2	Gene:	CG33090 / 34835	FlyBaseID:	FBgn0028916	Length:	948	Species:	Drosophila melanogaster
Sequence 2:	NP_001329211.1	Gene:	AT4G10060 / 826597	AraportID:	AT4G10060	Length:	922	Species:	Arabidopsis thaliana

Alignment Length:	961	Identity:	323/961 - (33%)
Similarity:	494/961 - (51%)	Gaps:	160/961 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KLQQQEESNEIAAVPKYGLKLKFDHVWPEK---RIQN---VRASIRQTLPMVPLVCRYAAYYWKV 95
            :||.|...||  .:|:.        .|..|   :::|   .:.|||..|.:.||..|...|..:.
plant    10 ELQTQMVGNE--RLPQV--------TWQRKLNSKVKNPSEFKMSIRDVLHLFPLGYRLWRYTKEE 64

  Fly    96 SREGRRVYMDYYYMENGKQIYGVPIGGIGGGTIGRGYAGEFCRFQMRPGIYEYNVVLANQFIVTI 160
            :::||....|.:...:.:..:|||:||||||:|||.|.|||.:|::.|.|.|...:|.|||.|.:
plant    65 AKKGRFSMYDIFKKRHVRGDHGVPLGGIGGGSIGRSYKGEFQQFKLFPKICEEAPILTNQFSVFV 129

  Fly   161 KDPKGCTIFQSLLSKCSTRDKTSDPDGDPDGERTKCQLPNCSSRAKQPLSAWHSNIEDTRCSYTG 225
            ..|.|.: :.::|  |.|:.|:.....:..|                 :.:|..|:|..:.:|..
plant   130 SRPGGLS-YSTVL--CPTKPKSVKGKTEDLG-----------------IESWDWNMEGDKSTYHA 174

  Fly   226 LYPRSWTEYDLSHYGVRLTCRQVSPVIPHEYRESSLPCAVFVWSVENVCDQERKVSITFTFKNGT 290
            |||||||.|:.....:|:..|||||.|||.|:|||||.:||.:::.|:..:|..|::.||::|..
plant   175 LYPRSWTVYNEPDPELRIVSRQVSPFIPHNYKESSLPVSVFEFTMSNLGKEEATVTLLFTWENSV 239

  Fly   291 GNKKQDAEGGAESQLISEGNAKGVSIRQKI--SEMPCSYNLACRVLPEISITRCPQFDPAGN--- 350
            |...........|.::.......:.:..|.  ...|.:|.:|.:...::.::.||.|..:|:
plant   240 GGASGLTGEHFNSTIMERDGVHAIVLHHKTGNGHPPVTYAIAAQETEDVHVSECPCFLVSGHSPK 304

  Fly   351 ---GEQLWAQLKEH---GQLSEHPTSEALKTKDIGVAVCGQVALKPMASHDLEFVLAWDMPKIQF 409
               .:::|.::|::   .:|:..|.|.:.....||.|:..:|.:.|.....:.|.|:||.|:::|
plant   305 EITAKEMWDEIKKNKSFDELNSEPGSPSRPGTSIGAAIAAKVKVPPGCDRTVTFSLSWDCPEVRF 369

  Fly   410 PRKMQTHTRYYTKYFDDSGDSGPRICEYALRQYSTWERLIDAWQRPILNDETLPDWYKCAIFNQL 474
            ..|  |:.|.|||::.:.||:..::...||..|..||..|:|||.|||:|.||||||:..:||:|
plant   370 NEK--TYHRRYTKFYGNLGDAAVKMARDALLNYVDWESQIEAWQSPILSDTTLPDWYRVTLFNEL 432

  Fly   475 YFISDGGTIWLK--------------------------------CDSSLGKELAYDDPRLAYGRF 507
            |:.:.|||||..                                |:.....:.:..:..:  |:|
plant   433 YYFNSGGTIWTDGLPPKESIERSKVTNTEQNDIVIDLFQKINAVCEQIYSPQSSNSEENI--GQF 495

  Fly   508 GYLEGHEYRMYNTYDVHFYASPALAHLWPNLQVSLQYDFKDAIAAELNDTRKMLYDGKVMPRKVK 572
            .||||.||.||||||||||:|.||..|:|.|.:|:|.||...:..:....:|::..|:.:.||:.
plant   496 IYLEGIEYLMYNTYDVHFYSSFALLSLFPKLALSIQRDFAATVLIQDPTKKKIMSSGEWVTRKLL 560

  Fly   573 NCVPHDLGDPDEEPFTLINCYNIHDVNDWKDLNTKFVLQVYRDYYVLNELAQAQSDNASKFSSIE 637
            ..||||:|..|  |:..:|.||..:.:.|||||.|||||||||....|:.:.|::...|.::::.
plant   561 GSVPHDIGLND--PWLELNEYNFFNTDRWKDLNAKFVLQVYRDVVATNDQSFAKAVWPSVYTAVA 623

  Fly   638 FIDKESLYELYSQDNKRKNSADEKQQNRKSASMYINETNGKVYLMDAIGYLKAMYASCKAIMERT 702
            ::|
plant   624 YLD-------------------------------------------------------------- 626

  Fly   703 IEYDKDNDGLIENTKMPDQTYDSWVMDGPSAYCSGLWLAALQAMSAMATILDQPNDCLRYQDILE 767
             ::|||.||:|||...||||||:|.:.|.||||.|||:|||||.||.|:|:.:....:.:....|
plant   627 -QFDKDEDGMIENEGFPDQTYDAWSVTGVSAYCGGLWVAALQAASAFASIVGENAVAIYFNAKYE 690

  Fly   768 KGKRSLEEKLWNGSYYRFDLSHS-HRDTIMADQLCGHWYLKSCGFDYEIYPKENVRTALKRIYDN 831
            |.| .:.||||||||:.:|.|.| ...:|:||||.|.||.::||.. .|..:|.::.||:.||:.
plant   691 KAK-IVYEKLWNGSYFNYDDSGSGSSSSILADQLAGQWYARACGLK-PITKEEWIKKALETIYEF 753

  Fly   832 NVMGFHEGNIGAANGFIANASEPTKPGHVDNSNIQAEEVWPGVVYALAATMIQEGMFEEAFQTAG 896
            |||....|..||.||.       :..|.||.:::.::|||.|..|::||.|||||..|:.||||.
plant   754 NVMKVKGGTRGAVNGM-------STEGKVDTNSLVSKEVWAGTTYSVAACMIQEGQREKGFQTAS 811

  Fly   897 GMYKTL-SQR-IGMNFETPEALYGEKRYRSIGYMRPLSIWSMQVALERRRA 945
            |:|:.: |.| :..:|:||||......|||:.|||||:||::|.||.|.::
plant   812 GIYEAIWSDRGLSCSFQTPEAWNMNDEYRSLCYMRPLAIWAIQWALTRTQS 862

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33090	NP_788055.2	GBA2_N	132..445	CDD:289023	92/323 (28%)
CG33090	NP_788055.2	DUF608	505..937	CDD:282531	169/434 (39%)
AT4G10060	NP_001329211.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	315	1.000	Domainoid score	I299
eggNOG	1	0.900	-	-		E1_COG4354
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	517	1.000	Inparanoid score	I295
OMA	1	1.010	-	-		QHG63864
OrthoDB	1	1.010	-	-		D207392at2759
OrthoFinder	1	1.000	-	-		FOG0003795
OrthoInspector	1	1.000	-	-		otm2806
orthoMCL	1	0.900	-	-		OOG6_105042
Panther	1	1.100	-	-	O	PTHR12654
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2650
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840