DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33090 and AT3G24180

DIOPT Version :9

Sequence 1:	NP_788055.2	Gene:	CG33090 / 34835	FlyBaseID:	FBgn0028916	Length:	948	Species:	Drosophila melanogaster
Sequence 2:	NP_001030757.1	Gene:	AT3G24180 / 822004	AraportID:	AT3G24180	Length:	950	Species:	Arabidopsis thaliana

Alignment Length:	990	Identity:	330/990 - (33%)
Similarity:	473/990 - (47%)	Gaps:	207/990 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 LKFD------HVWPEKRIQNVRASI--------RQTLPMVPLVCRYAAYYWKVSREGRRVYMDYY 107
            |.||      |.|  :|..|..|:|        |:.:.||.|..|..:|..:.:..||:..:|.:
plant    28 LDFDSAAPPPHAW--RRRLNCHANILKEFTITFREAIKMVRLGIRLWSYVREEASHGRKAPIDPF 90

  Fly   108 YMENGK--QIYGVPIGGIGGGTIGRGYAGEFCRFQMRPGIYEYNVVLANQFIVTIKDPKGCTIFQ 170
            ..||.|  ...|||:||:|.|:|.||:.|||.::|:.||..:.:.:::|||.:.|....|...:.
plant    91 TKENCKPSASQGVPLGGMGSGSISRGFRGEFKQWQITPGTCDPSPMMSNQFSIFISRDGGHKKYA 155

  Fly   171 SLLSK------CSTRDKTSDPDGDPDGERTKCQLPNCSSRAKQPLSAWHSNIEDTRCSYTGLYPR 229
            |:||.      ..:|||                          .||:|..|:.....:|..|:||
plant   156 SVLSPGQHGSLGKSRDK--------------------------GLSSWGWNLNGQHSTYHALFPR 194

  Fly   230 SWTEYDLSHYG-----VRLTCRQVSPVIPHEYRESSLPCAVFVWSVENVCDQERKVSITFTFKNG 289
            :||.||    |     ::::|||:||.||:.||:||||.||||:::.|...:..|||:.||:.|.
plant   195 AWTIYD----GEPDPELKISCRQISPFIPNNYRDSSLPAAVFVYTLVNTGKERAKVSLLFTWANS 255

  Fly   290 TGNKKQDAEGGAESQLISEGNAKGVSIRQKISE--MPCSYNLACRVLPEISITRCPQF----DPA 348
            .|.....:.|......|.|....||.:..|..:  .|.::.:|......:::|..|.|    |.:
plant   256 MGGTSHMSGGHVNEPFIGEDGVSGVLLHHKTGKGNPPVTFAIAASETQNVNVTVLPCFGLSEDSS 320

  Fly   349 GNGEQLWAQLKEHGQLSEH-----PTSEALKTKDIGVAVCGQVALKPMASHDLEFVLAWDMPKIQ 408
            ...:.:|..:::.|:..:.     |::.:|....|..||.....::......:.|.|:|..||::
plant   321 FTAKDMWDTMEQDGKFDQENFNSGPSTPSLAGDTICAAVSASAWVEAHGKCTVSFALSWSSPKVK 385

  Fly   409 FPRKMQTHTRYYTKYFDDSGDSGPRICEYALRQYSTWERLIDAWQRPILNDETLPDWYKCAIFNQ 473
            | .|..|:.|.|||::..|..:...:...||..|..||..|:|||.|||.||.||:|||..:||:
plant   386 F-SKGSTYDRRYTKFYGTSPRAALDLVHDALTNYKRWEEDIEAWQNPILRDERLPEWYKFTLFNE 449

  Fly   474 LYFISDGGTIWLKCDSS--------------LGKE------------------------------ 494
            |||:..|||:|:  |||              ||..
plant   450 LYFLVAGGTVWI--DSSSLNANGNSQHQQSGLGNSDGKVGGLDINDQRNDLGNGNSVGVKSNDEV 512

  Fly   495 --------LAYDDPRL----AYGRFGYLEGHEYRMYNTYDVHFYASPALAHLWPNLQVSLQYDFK 547
                    |..|.|.:    ..|||.||||.||.|:.|||||||||.||..|:|.:::::|.||.
plant   513 SAIHNRNGLFVDTPHVDDGDDVGRFLYLEGVEYVMWCTYDVHFYASYALLMLFPKIELNIQRDFA 577

  Fly   548 DAIAAELNDTRKMLYDGKVMPRKVKNCVPHDLGDPDEEPFTLINCYNIHDVNDWKDLNTKFVLQV 612
            .|:.:|.....|.|.:|.|..|||:..||||||..|  |:..:|.|||||.:.|||||.||||||
plant   578 KAVLSEDGRKVKFLAEGNVGIRKVRGAVPHDLGMHD--PWNEMNAYNIHDTSRWKDLNPKFVLQV 640

  Fly   613 YRDYYVLNELAQAQSDNASKFSSIEF-IDKESLYELYSQDNKRKNSADEKQQNRKSASMYINETN 676
            |||:....:              .:| ||
plant   641 YRDFAATGD--------------YQFGID------------------------------------ 655

  Fly   677 GKVYLMDAIGYLKAMYASCKAIMERTIEYDKDNDGLIENTKMPDQTYDSWVMDGPSAYCSGLWLA 741
                          ::.:.:|.||...::|:|||.||||...||||||:|.:.|.||||..||||
plant   656 --------------VWPAVRAAMEYMEQFDRDNDDLIENDGFPDQTYDTWTVHGVSAYCGCLWLA 706

  Fly   742 ALQAMSAMATILDQPNDCLRYQDILEKGKRSLEEKLWNGSYYRFDL-SHSHRDTIMADQLCGHWY 805
            ||||.:|||..:.........::.....|.:||.|||||||:.:|. |.|:..:|..|||.|.||
plant   707 ALQAAAAMALQIGDKFFAELCKNKFLNAKAALETKLWNGSYFNYDSGSSSNSKSIQTDQLAGQWY 771

  Fly   806 LKSCGFDYEIYPKENVRTALKRIYDNNVMGFHEGNIGAANGFIANASEPTKPGHVDNSNIQAEEV 870
            ..|.|.. .::.:..:|:.:::|:|.|||....|.:||.||...:       |.||::.:|:.|:
plant   772 AASSGLP-PLFEESKIRSTMQKIFDFNVMKTKGGKMGAVNGMHPD-------GKVDDTCMQSREI 828

  Fly   871 WPGVVYALAATMIQEGMFEEAFQTAGGMYKT--LSQRIGMNFETPEALYGEKRYRSIGYMRPLSI 933
            |.||.||.|||||..||.|:.|.||.|::..  ..:..|..|:|||....:..|||:.|||||:|
plant   829 WTGVTYAAAATMILSGMEEQGFTTAEGIFTAGWSEEGFGYWFQTPEGWTMDGHYRSLIYMRPLAI 893

  Fly   934 WSMQVALERRRAQRD 948
            |.||.||...:|..|
plant   894 WGMQWALSLPKAILD 908

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33090	NP_788055.2	GBA2_N	132..445	CDD:289023	90/334 (27%)
CG33090	NP_788055.2	DUF608	505..937	CDD:282531	170/435 (39%)
AT3G24180	NP_001030757.1	Glyco_hydr_116N	102..418	CDD:371967	99/346 (29%)
AT3G24180	NP_001030757.1	DUF608	535..896	CDD:368056	170/434 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	315	1.000	Domainoid score	I299
eggNOG	1	0.900	-	-		E1_COG4354
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10859
Inparanoid	1	1.050	517	1.000	Inparanoid score	I295
OMA	1	1.010	-	-		QHG63864
OrthoDB	1	1.010	-	-		D207392at2759
OrthoFinder	1	1.000	-	-		FOG0003795
OrthoInspector	1	1.000	-	-		otm2806
orthoMCL	1	0.900	-	-		OOG6_105042
Panther	1	1.100	-	-	LDO	PTHR12654
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2650
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840