Protein Alignment CG33090 and Gba2

DIOPT Version :10

• Sequence 1: NP_788055.2
• Gene: CG33090 / 34835
• FlyBaseID: FBgn0028916
• Length: 948
• Species: Drosophila melanogaster
• Sequence 2: NP_766280.2
• Gene: Gba2 / 230101
• MGIID: 2654325
• Length: 918
• Species: Mus musculus
• Alignment Length: 979
• Identity: 389/979 - (39%)
• Similarity: 537/979 - (54%)
• Gaps: 154/979 - (15%)

  Fly    22 VGIAESASAVF-----------------------QEKLKLQQQEESNEIAA----------VPKY 53
            ||.||..|.|:                       |::......|:|.::.|          ||.:
Mouse    11 VGCAERDSQVYCEDTGGTEAVRVTDCGSPEDSGPQDEPSYCNSEDSGQLMASYEGKARGYQVPPF 75

  Fly    54 GLKLKFDHVWPEKR--IQNVRASIRQTLPMVPLVCRYAA-YYWKVSREGRRVYMDYYYMENGKQI 115
            |.::...|.:.|||  .|....|:...:..:.:..||.. :|.|...|.:..::|.......:||
Mouse    76 GWRICLAHEFAEKRRPFQANNISLSNLVKHLGMGLRYLKWWYRKTHVEKKTPFIDMLNSLPLRQI 140

  Fly   116 YGVPIGGIGGGTIGRGYAGEFCRFQMRPGIYEYNVVLANQFIVTIKDPKGCTIFQSLLSKCSTRD 180
            ||.|:||||||||.||:.|:|||:|:.||:|::..|:|:||||.:: ..|.|::|.:||
Mouse   141 YGCPLGGIGGGTITRGWRGQFCRWQLNPGMYQHQTVIADQFIVCLR-RDGRTVYQQVLS------ 198

  Fly   181 KTSDPDGDPDGERTKCQLPNCSSRAKQPLSAWHSNIEDTRCSYTGLYPRSWTEYDLSHYGVRLTC 245
                           .:|||.       |.:|:..:......|..||||:||.|.|....|.|||
Mouse   199 ---------------LELPNV-------LRSWNWGLCGYFAFYHALYPRAWTVYQLPGQNVTLTC 241

  Fly   246 RQVSPVIPHEYRESSLPCAVFVWSVENVCDQERKVSITFTFKNGTGNKKQDAEGGA--ESQLISE 308
            |||:|::||:|::||||..||||.|||..|:...|||||:.:||.|. :.||.|..  |...:.:
Mouse   242 RQVTPILPHDYQDSSLPVGVFVWDVENEGDETLDVSITFSMRNGLGG-EDDAAGSLWNEPFRLEQ 305

  Fly   309 G--NAKGVSIRQKISEMPCSYNLACRVLPEISITRCPQFDPAGNGEQLWAQLKEHGQLSEHPTSE 371
            |  ..:|:.:.......|.:..:|.|...:.::|....|||.|.|:|:|..|.:.||| :.|..:
Mouse   306 GGTTVQGLLLHHPTPPNPYTMAVAARCTADTTVTHTTAFDPNGTGQQVWQDLLQDGQL-DSPAGQ 369

  Fly   372 ALKT---KDIGVAVCGQVALKPMASHDLEFVLAWDMPKIQFPRKMQTHTRYYTKYFDDSGDSGPR 433
            :..|   :.|..|||....|.|.:...|||.||||||||.|..|.|.|.|.||::|...||..|.
Mouse   370 STPTQKGEGIAGAVCVSSKLLPRSRCCLEFSLAWDMPKIMFGAKSQVHYRRYTRFFGSDGDVAPA 434

  Fly   434 ICEYALRQYSTWERLIDAWQRPILNDETLPDWYKCAIFNQLYFISDGGTIWLKCDS-SLGKELAY 497
            :..|||..|:.||..|.|||.|:|:|.|||.|||.|:||:|||::||||:||:..: ||.:.|..
Mouse   435 LSHYALCHYADWEDRISAWQNPVLDDRTLPAWYKSALFNELYFLADGGTVWLEVPADSLPEGLGG 499

  Fly   498 DDPRLA-----YGRFGYLEGHEYRMYNTYDVHFYASPALAHLWPNLQVSLQYDFKDAIAAELNDT 557
            ...:|.     |||||||||.|||||||||||||||.||..|||.|::|||||...|...|....
Mouse   500 SMRQLRSTLQDYGRFGYLEGQEYRMYNTYDVHFYASFALVMLWPKLELSLQYDMALATLKEDLTR 564

  Fly   558 RKMLYDGKVMPRKVKNCVPHDLGDPDEEPFTLINCYNIHDVNDWKDLNTKFVLQVYRDYYVLNEL 622
            |:.|..|.|.|.|.:|.:|||:||||:||:..:|.|.|||..||||||.|||||:|||||:
Mouse   565 RRYLMSGVVAPVKRRNVIPHDIGDPDDEPWLRVNAYLIHDTADWKDLNLKFVLQIYRDYYL---- 625

  Fly   623 AQAQSDNASKFSSIEFIDKESLYELYSQDNKRKNSADEKQQNRKSASMYINETNGKVYLMDAIGY 687
                                              :.|:                         |:
Mouse   626 ----------------------------------TGDQ-------------------------GF 631

  Fly   688 LKAMYASCKAIMERTIEYDKDNDGLIENTKMPDQTYDSWVMDGPSAYCSGLWLAALQAMSAMATI 752
            |:.|:..|.|:||..:::|||.||||||....|||||:||..||||||.||||||:..|..||.:
Mouse   632 LEDMWPVCLAVMESEMKFDKDQDGLIENGGYADQTYDAWVTTGPSAYCGGLWLAAVAVMVQMAVL 696

  Fly   753 LDQPNDCLRYQDILEKGKRSLEEKLWNGSYYRFD-LSHSHRDTIMADQLCGHWYLKSCGF---DY 813
            ....:...|:..||.:|:.:.|..||||.||.:| .||....:||:||..|.|:|::||.   |.
Mouse   697 CGAQDVQERFASILCRGREAYERLLWNGRYYNYDSSSHPQSRSIMSDQCAGQWFLRACGLGEGDT 761

  Fly   814 EIYPKENVRTALKRIYDNNVMGFHEGNIGAANGFIANASEPTKPGHVDNSNIQAEEVWPGVVYAL 878
            |::|..:|..||:.|::.||..|..|.:||.||...:       |..|.|::|::|||.||||.|
Mouse   762 EVFPTLHVVRALQTIFELNVQAFAGGAMGAVNGMHPH-------GVPDRSSVQSDEVWVGVVYGL 819

  Fly   879 AATMIQEGMFEEAFQTAGGMYKTLSQRIGMNFETPEALYGEKRYRSIGYMRPLSIWSMQVALERR 943
            ||||||||:..|.|:||.|.|:|:.:|:|:.|:||||...::.:||:.||||||||:||:||:::
Mouse   820 AATMIQEGLTWEGFRTAEGCYRTVWERLGLAFQTPEAYCQQQVFRSLAYMRPLSIWAMQLALQQQ 884

  Fly   944 RAQR 947
            :.::
Mouse   885 QHKK 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33090	NP_788055.2	Glyco_hydr_116N	132..445	CDD:463496	119/319 (37%)
		DUF608	505..936	CDD:461391	194/434 (45%)
Gba2	NP_766280.2	Glyco_hydr_116N	157..446	CDD:463496	119/319 (37%)
		DUF608	512..875	CDD:461391	192/432 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	886..918		0/3 (0%)