Protein Alignment CG33090 and R08F11.1

DIOPT Version :9

• Sequence 1: NP_788055.2
• Gene: CG33090 / 34835
• FlyBaseID: FBgn0028916
• Length: 948
• Species: Drosophila melanogaster
• Sequence 2: NP_001317760.1
• Gene: R08F11.1 / 187703
• WormBaseID: WBGene00019965
• Length: 819
• Species: Caenorhabditis elegans
• Alignment Length: 912
• Identity: 327/912 - (35%)
• Similarity: 481/912 - (52%)
• Gaps: 131/912 - (14%)

  Fly    54 GLKLKFDHVWPEKRIQNVR---ASIRQTLPMVPLVCRYAAY----YWKVSREGRRVYMDYYYMEN 111
            |.|.:.|.: ||  ..|.|   ..::.::.::||..|.|.:    :|    .||..::|.:.:..
 Worm    14 GWKARGDRI-PE--FPNPRPFFPRLKHSIKLIPLFVRVALHTFVEWW----NGREAFIDIFNVFR 71

  Fly   112 GKQIYGVPIGGIGGGTIGRGYAGEFCRFQMRPGIYEY-NVVLANQFIVTIKDPKGC-TIFQSLLS 174
            .....|||:||||.|:||..:.|.|.||.:.|||.|. .....||||||:...|.. .|:||:||
 Worm    72 HFTYTGVPLGGIGCGSIGTDFRGGFNRFSIIPGIKEQTETQKCNQFIVTVHSKKTFELIYQSILS 136

  Fly   175 KCSTRDKTSDPDGDPDGERTKCQLPNCSSRAKQPLSAWHSNI--EDTRCSYTGLYPRSWTEYDLS 237
                                      |:......|..|.:.|  ||.|  |.||:||:|.|:.|.
 Worm   137 --------------------------CAEFPATVLPKWDTTIPAEDVR--YRGLFPRAWQEFRLG 173

  Fly   238 HYGVRLTCRQVSPVIPHEYRESSLPCAVFVWSVENVCDQERKVSITFTFKNGTGNKKQDAEGGAE 302
            ..||.:....:|||||.:|.:||||.|.|.:.|.|...:|.:||||.:|:|||||:|.:.|...:
 Worm   174 SSGVTVVVEHLSPVIPGDYSDSSLPLANFEFHVFNDSYEEVEVSITMSFRNGTGNRKWNDENLCQ 238

  Fly   303 SQLISEGNAKGVSIRQKISEMPCSYNLACRVLPEISITRCPQFDPAGNGEQLWAQLKEHGQLS-- 365
            ||.|.:......::...:..||.:|.:.........:|.| .|||.|.|.:||:.|:.:|.||
 Worm   239 SQKIQKDTMVVRTLAHTVKGMPVTYAIGTEEKNGSKVTTC-LFDPNGTGGRLWSDLEAYGHLSSY 302

  Fly   366 EHPTSEALKTKDIGVAVCGQVALKPMASHDLEFVLAWDMPKIQFPRKMQTHTRYYTKYFD--DSG 428
            :|..|   |.|::|:|||....:.|..:|:.:|.|.|.||::.|....:.:.|.|.::|:  |:.
 Worm   303 DHLPS---KPKELGIAVCSSFFVPPDGAHNTQFSLTWYMPQVHFGTAERFYNRRYCRFFNGPDAD 364

  Fly   429 DSGPRICEYALRQYSTWERLIDAWQRPILNDETLPDWYKCAIFNQLYFISDGGTIWL------KC 487
            :....||.:.|:.:|||::.|:.||.|:|||:.||:|||.||||:||:|.||.|:|.      |.
 Worm   365 EVTAAICRHGLQNFSTWQKKIEDWQAPVLNDQKLPEWYKSAIFNELYYIVDGSTVWFEYDPDWKT 429

  Fly   488 DSSLGKELAYDDPRLAYGRFGYLEGHEYRMYNTYDVHFYASPALAHLWPNLQVSLQYDFKDAIAA 552
            :.||..|.. :.....||||||:|..||.|.||||||||:|.|:...||.:::|:|.||.|.:..
 Worm   430 EESLMSEQT-EKQFKEYGRFGYMESWEYFMINTYDVHFYSSWAILKNWPQIEMSMQLDFADQMDR 493

  Fly   553 ELNDTRKMLYDGKVMPRKVKNCVPHDLGDPDEEPFTLINCYNIHDVNDWKDLNTKFVLQVYRDYY 617
            ..|:....|.||:.|..|..:.:|||:|.|..:|:...|.|.:||...|||||.|||:..|||:
 Worm   494 VDNNIATSLADGEQMTIKSVDRIPHDMGHPMADPWIHTNAYILHDTGRWKDLNLKFVISCYRDW- 557

  Fly   618 VLNELAQAQSDNASKFSSIEFIDKESLYELYSQDNKRKNSADEKQQNRKSASMYINETNGKVYLM 682
                                     .|.||.|:                         .|:|
 Worm   558 -------------------------KLIELGSE-------------------------KGQV--- 569

  Fly   683 DAIGYLKAMYASCKAIMERTIE-YDKDNDGLIENTKMPDQTYDSWVMDGPSAYCSGLWLAALQAM 746
                 |:.....|..|::..:| :||||||:|||....|||||.|.|.|.||||..||:|||.:.
 Worm   570 -----LEFFLGKCTKIVDGALECWDKDNDGMIENDGFADQTYDVWKMTGTSAYCGSLWIAALSSY 629

  Fly   747 SAMATILDQPNDCLRYQDILEKGKRSLEEKLWNGSYYRFDLSHSHRDTIMADQLCGHWYLKSCGF 811
            ..|......|..  .|::.||....:...|||||::::||....:...:|||||||.|.:.:...
 Worm   630 IEMLKQSGLPTK--HYEEKLEMAYDAYIGKLWNGTFFKFDELPENSKIVMADQLCGFWAMTAMDE 692

  Fly   812 DYEIYPKENVRTALKRIYDNNVMGFHEGNIGAANGFIANASEPTKPGHVDNSNIQAEEVWPGVVY 876
            ..:| .|:.:::||..|:..||..::.|..||.||::.:.       .||.|:||:||||.|:.|
 Worm   693 PVQI-SKDKMKSALDTIFKYNVQMYNNGRCGAVNGYLTSE-------RVDGSSIQSEEVWAGITY 749

  Fly   877 ALAATMIQEGMFEEAFQTAGGMYKTLSQRIGMNFETPEALYGEKRYRSIGYMRPLSIWSMQVALE 941
            ||:|.||::||.|:||:|:.|:::::..|..:.::||||:..:..||::|||||||||::|.||:
 Worm   750 ALSAMMIEKGMDEQAFKTSEGLFESIWHRFPLQYQTPEAITSDGMYRALGYMRPLSIWAIQHALD 814

  Fly   942 RR 943
            ||
 Worm   815 RR 816

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33090	NP_788055.2	GBA2_N	132..445	CDD:289023	107/320 (33%)
		DUF608	505..937	CDD:282531	160/432 (37%)
R08F11.1	NP_001317760.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156054
Domainoid	1	1.000	208	1.000	Domainoid score	I1667
eggNOG	1	0.900	-	-		E1_COG4354
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H10859
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4511
OMA	1	1.010	-	-		QHG63864
OrthoDB	1	1.010	-	-		D207392at2759
OrthoFinder	1	1.000	-	-		FOG0003795
OrthoInspector	1	1.000	-	-		otm14215
orthoMCL	1	0.900	-	-		OOG6_105042
Panther	1	1.100	-	-	LDO	PTHR12654
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2650
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.670