| Sequence 1: | NP_788055.2 | Gene: | CG33090 / 34835 | FlyBaseID: | FBgn0028916 | Length: | 948 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001229766.1 | Gene: | AP2A2 / 161 | HGNCID: | 562 | Length: | 940 | Species: | Homo sapiens |
| Alignment Length: | 502 | Identity: | 84/502 - (16%) |
|---|---|---|---|
| Similarity: | 152/502 - (30%) | Gaps: | 195/502 - (38%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 337 ISITRC--PQFDPAGNGEQLWAQLKEHGQLSEHPTSEALKTKDIGVAVCGQVALKPMASHDLEFV 399
Fly 400 LAWDMPKI---------QFPRKMQTHTRYYTKYFDDSGDSGPRICEYALRQYS------------ 443
Fly 444 ---TWERLIDAWQRPILNDETLPDWYKCAIFNQLYFISDGGTIWLKCDSSLGKELAYDDPRLAYG 505
Fly 506 RFGYLEGHEYRMYN-------------TYDVHFYASPAL-----------AHLWPN-LQVSLQYD 545
Fly 546 FKDAIAAELNDTRKMLYDGKVMPRKVKNCVPHD-----------LGDPDEEPFTLINCYNIHDVN 599
Fly 600 DWKDLNTK-FVLQVYRDYYVLNELAQAQSDNASKFSSIEFID-----KESLYELYSQDNKRKNSA 658
Fly 659 DEKQQNRKSASMYINETNGKVYLMDAIGYLKAMYASCKAIMERTIEY-----DKDNDGL------ 712
Fly 713 --------IENTKMPDQTYDSWVMDGPSAYCSGLWLAALQAMSAMAT 751 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG33090 | NP_788055.2 | GBA2_N | 132..445 | CDD:289023 | 24/133 (18%) |
| DUF608 | 505..937 | CDD:282531 | 52/308 (17%) | ||
| AP2A2 | NP_001229766.1 | Lipid-binding | 5..80 | ||
| Phosphatidylinositol 3,4,5-trisphosphate binding. /evidence=ECO:0000250|UniProtKB:P18484 | 11..12 | ||||
| Adaptin_N | 29..591 | CDD:279882 | 69/425 (16%) | ||
| Phosphatidylinositol 3,4,5-trisphosphate binding. /evidence=ECO:0000250|UniProtKB:P18484 | 57..61 | ||||
| Cnd1 | <163..>235 | CDD:289487 | |||
| HEAT repeat | 332..355 | CDD:293787 | 5/31 (16%) | ||
| HEAT repeat | 369..398 | CDD:293787 | 4/52 (8%) | ||
| HEAT repeat | 408..434 | CDD:293787 | 4/25 (16%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 613..682 | 13/54 (24%) | |||
| Alpha_adaptinC2 | 718..821 | CDD:197886 | |||
| Alpha_adaptin_C | 827..935 | CDD:280460 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG4354 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||