Protein Alignment CG33090 and gba2

DIOPT Version :10

• Sequence 1: NP_788055.2
• Gene: CG33090 / 34835
• FlyBaseID: FBgn0028916
• Length: 948
• Species: Drosophila melanogaster
• Sequence 2: XP_031762709.1
• Gene: gba2 / 100145361
• XenbaseID: XB-GENE-5799150
• Length: 785
• Species: Xenopus tropicalis
• Alignment Length: 924
• Identity: 333/924 - (36%)
• Similarity: 470/924 - (50%)
• Gaps: 207/924 - (22%)

  Fly    50 VPKYGLKLKFDHVWPEKR--IQNVRASIRQTLPMVPLVCRYAAYYWKVSREGRRVYMD----YYY 108
            ||.:|.::...|.:.|||  .|....|..|.:..:|:..||..::.      |:.|||    :..
 Frog    20 VPAHGWRICLAHEFEEKRKPFQLANVSPCQMITHLPMGIRYLLWWC------RKTYMDRKAPFID 78

  Fly   109 MENG---KQIYGVPIGGIGGGTIGRGYAGEFCRFQMRPGIYEYNVVLANQFIVTIKDPKGCTIFQ 170
            |.|.   :||||:.:              .||.
 Frog    79 MLNSIPLRQIYGMSM--------------HFCL-------------------------------- 97

  Fly   171 SLLSKCSTRDKTSDPDGDPDGERTKCQLPNCSSRAKQPLSAWHSNIEDTRCSYTGLYPRSWTEYD 235
                                |...:|..|...|.        ||..:      .||...||
 Frog    98 --------------------GAAGQCDGPGTMSA--------HSEAQ------MGLVLGSW---- 124

  Fly   236 LSHY--GVRLTCRQVSPVIPHEYRESSLPCAVFVWSVENVCDQERKVSITFTFKNGTGNKKQDA- 297
              |:  |....|          :.:||||.||.||.:||..|:|.:|:|.||.:||:|.:...|
 Frog   125 --HHKNGTIKQC----------HLDSSLPLAVLVWDIENGGDEEMEVTIMFTLRNGSGTRSDRAG 177

  Fly   298 -EGGAESQLISEG-NAKGVSIRQKISEMPCSYNLACRVLPEISITRCPQFDPAGNGEQLWAQLKE 360
             ......||..:| :.:|:.:....:..|.:..:|.|..|.:.::.|.||||.|.|:::|..|.|
 Frog   178 NHWNEPFQLQKDGESVRGMLLHHCTATNPYTMGVAVRERPGVCVSHCTQFDPTGLGQEVWKDLLE 242

  Fly   361 HGQLSE--HPTSEALKTKDIGVAVCGQVALKPMASHDLEF-VLAWDMPKIQFPRKMQTHTRYYTK 422
            .|:|:.  .|:....|.|....||....:|.|.:...||| .|:||||.|:|....:.|.|.||:
 Frog   243 DGRLNSAPGPSPPTAKGKKTAAAVAAGCSLPPRSRETLEFWGLSWDMPNIRFGAGQREHHRRYTR 307

  Fly   423 YFDDSGDSGPRICEYALRQYSTWERLIDAWQRPILNDETLPDWYKCAIFNQLYFISDGGTIWLKC 487
            :|...||:.|.:|.|.|..:..||:.|:|||.|||.:..||.|||.|:||:|||::||||:|::.
 Frog   308 FFGCQGDAAPALCHYGLTHFVGWEQKIEAWQEPILQNGDLPAWYKSALFNELYFMADGGTVWVEV 372

  Fly   488 -----DSSLGKELAYDDPRL-----AYGRFGYLEGHEYRMYNTYDVHFYASPALAHLWPNLQVSL 542
                 |.:|.:....|.|.:     .||||.||||.|||||||||||||||.||..|||.|::||
 Frog   373 SAADDDDNLMRRGCKDLPGMKDVLQEYGRFAYLEGQEYRMYNTYDVHFYASFALIMLWPQLEISL 437

  Fly   543 QYDFKDAIAAELNDTRKMLYDGKVMPRKVKNCVPHDLGDPDEEPFTLINCYNIHDVNDWKDLNTK 607
            |||...::..|..:.||.|..|.|.|.|.::.||||:||||:||:..:|.|.|||..:|||||.|
 Frog   438 QYDMAASVLQEDPELRKYLMSGTVAPVKSRSVVPHDVGDPDDEPWQKLNAYLIHDTANWKDLNLK 502

  Fly   608 FVLQVYRDYYVLNELAQAQSDNASKFSSIEFIDKESLYELYSQDNKRKNSADEKQQNRKSASMYI 672
            |||||||||::..:..
 Frog   503 FVLQVYRDYHITKDTT------------------------------------------------- 518

  Fly   673 NETNGKVYLMDAIGYLKAMYASCKAIMERTIEYDKDNDGLIENTKMPDQTYDSWVMDGPSAYCSG 737
                          ||:.|::.|:.:||.::::|:|.||||||:...|||||.|||.|||:||.|
 Frog   519 --------------YLRDMWSVCQTVMETSLKFDEDGDGLIENSGFADQTYDDWVMTGPSSYCGG 569

  Fly   738 LWLAALQAMSAMATILDQPNDCLRYQDILEKGKRSLEEKLWNGSYYRFDL-SHSHRDTIMADQLC 801
            |||||:..|..||.:|.......::.|||.:||.:.|:.||||.||.||. ...:.:::|.||..
 Frog   570 LWLAAVCMMCKMAEVLGDGAAQEKFTDILHRGKAAFEKLLWNGKYYNFDCGDQPYSNSVMVDQCA 634

  Fly   802 GHWYLKSCGF---DYEIYPKENVRTALKRIYDNNVMGFHEGNIGAANGFIANASEPTKP-GHVDN 862
            |:|:|::||.   :.|::||::|.:||:.|::.||..|.:|.:||.||.        :| |..|.
 Frog   635 GNWFLRACGLGAGESEVFPKDHVVSALRTIFELNVKQFADGQMGAVNGM--------RPDGTTDT 691

  Fly   863 SNIQAEEVWPGVVYALAATMIQEGMFEEAFQTAGGMYKTLSQRIGMNFETPEALYGEKR-YRSIG 926
            |::|::|||.||||.||||||.||:.:|.|.||.|.|:|:.:|:||:|:|||| |.||: :||:.
 Frog   692 SSVQSDEVWIGVVYGLAATMIHEGLVQEGFATAEGCYRTVWERLGMSFQTPEA-YCEKQVFRSLA 755

  Fly   927 YMRPLSIWSMQVAL 940
            ||||||||:||:||
 Frog   756 YMRPLSIWAMQLAL 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33090	NP_788055.2	Glyco_hydr_116N	132..445	CDD:463496	83/320 (26%)
		DUF608	505..936	CDD:461391	193/436 (44%)
gba2	XP_031762709.1	Glyco_hydr_116N	<137..330	CDD:463496	68/192 (35%)
		DUF608	400..765	CDD:461391	193/436 (44%)