DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15286 and Kcmf1

DIOPT Version :9

Sequence 1:	NP_001285929.1	Gene:	CG15286 / 34834	FlyBaseID:	FBgn0028531	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001121664.1	Gene:	Kcmf1 / 684322	RGDID:	1591490	Length:	381	Species:	Rattus norvegicus

Alignment Length:	485	Identity:	107/485 - (22%)
Similarity:	167/485 - (34%)	Gaps:	165/485 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 MNRHERIECKGCGKRSLTFRCYRCLSCQDFDICEECYDNDFTTSTHPFDHPVVCVLIPADVELYF 67
            |:|||.:.|..|.|.:...|.|:||.|.|:|:|..||::..||:.|..|||:.|:|...|.:||:
  Rat     1 MSRHEGVSCDACLKGNFRGRRYKCLICYDYDLCASCYESGATTTRHTTDHPMQCILTRVDFDLYY 65

  Fly    68 GGEYISNYPPQSYRCPYCKRWGFNESTFLEHVSAMHPDASPLLVSTMVGLF--------EQQQAA 124
            |||..|...|||:.||||.:.|:.|::..|||::.|.:.|..::..:....        ....||
  Rat    66 GGEAFSVEQPQSFTCPYCGKMGYTETSLQEHVTSEHAETSTEVICPICAALPGGDPNHVTDDFAA 130

  Fly   125 RLFLENEQLASIAVAATSRNELMRRPEGSMALYLEPLNRDGSYRRVVERNNEDRSRRLSPDGRDR 189
            .|.||:                 |.|        ..|:.....|.|         ||:...||.
  Rat   131 HLTLEH-----------------RAP--------RDLDESSGVRHV---------RRMFHPGRG- 160

  Fly   190 LQALVRERYSRIARRSAARVGNMTSRPLLAPAPGDGSRLSGIQESIEAGQGIRNVIVEELSTSNY 254
             ....|.|.|.:...|::..|..:|:...:|:..:.  :..|.|.:....|:|.....:|::|
  Rat   161 -LGGPRARRSNMHFTSSSTGGLSSSQSSYSPSSREA--MDPIAELLSQLSGVRRSAGGQLNSS-- 220

  Fly   255 DPPFTINASASAILEQQQQQQVMGPSPNAAAPPIVTHPSLIEMMRFYDEAGLQPFPASSRRVIRT 319
                  ..|||.:.:.|.|.|                                         :..
  Rat   221 ------GPSASQLQQLQMQLQ-----------------------------------------LER 238

  Fly   320 RHANPA-QPAANIGNNTRSINVYGPTSAFTQASHNTRSLTAPDLFSLDERYRISRMPMFQANPGA 383
            :||..| |......|.:|..|....|:..|||:....:...                  :.:|.|
  Rat   239 QHAQAARQQLETARNASRRTNTSSVTTTITQATATANTANT------------------ENSPQA 285

  Fly   384 LHRQGTGTRALDTRAVEFSEFPPEETELPLILGTSTIEDPSKLTKQRDQERRRFLCYRFTTPRSS 448
            ||..                                                :||..|...|:.|
  Rat   286 LHNS------------------------------------------------QFLLTRLNDPKMS 302

  Fly   449 KRPQNHFLLQRAE---FVSQVLYSALCDED 475
            :..:.....:||:   ||.::|.|.|..|:
  Rat   303 EAERQSMESERADRSLFVQELLLSTLVREE 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15286	NP_001285929.1	ZZ_PCMF_like	9..57	CDD:239078	19/47 (40%)
CG15286	NP_001285929.1	zf-Di19	78..>107	CDD:283297	12/28 (43%)
Kcmf1	NP_001121664.1	ZZ_PCMF_like	7..55	CDD:239078	19/47 (40%)
Kcmf1	NP_001121664.1	zf-Di19	76..137	CDD:398954	18/77 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354123
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004459
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.700