Sequence 1: | NP_001260456.1 | Gene: | Dyrk2 / 34831 | FlyBaseID: | FBgn0016930 | Length: | 757 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_004705.1 | Gene: | DYRK1B / 9149 | HGNCID: | 3092 | Length: | 629 | Species: | Homo sapiens |
Alignment Length: | 577 | Identity: | 203/577 - (35%) |
---|---|---|---|
Similarity: | 284/577 - (49%) | Gaps: | 122/577 - (21%) |
- Green bases have known domain annotations that are detailed below.
Fly 162 MTPSELVKKFRNY----LTDLEFEELKVYK---EVWYFGQHASKNYNKPAPTAN-----TTNLGY 214
Fly 215 DDDNGNYKIIEHDHIAFRYEILEVIGKGSFGQVIRALDHKTNTHVAIKIIRNKKRFLNQAVVELN 279
Fly 280 ILDELREKDADGSHNVIHMLDYTYFRKHLCITFELMSLNLYELIKKNNYNGFSMSLIRRFCNSIV 344
Fly 345 KCLRLLY----KENIIHCDLKPENILLKQRGSSSIKVIDFGSSCYVDRKIYTYIQSRFYRSPEVI 405
Fly 406 LGLQYGTAIDMWSLGCILAELYTGFPLFPGENEVEQLACIMEVLGLPPKVLISVARRRRLFFDSR 470
Fly 471 DAPR-CITNTKGRKR---SPGSKSLAHIL----------------HCQDRY--FIDFLQRCLEWD 513
Fly 514 PAERMTPDEAAHHEFLQ----------PSASSRHRS------CRMSSS----SSSSGLNSVSQKS 558
Fly 559 SCYSFSEISPGTNGPVVASITSTTAVHNAAIATTTKSRQQPPSQSHGHAQSNGHLPDIKLSASDK 623
Fly 624 YNSMQKVAVRSKITSSVSDLESVQQYSLHRIYGGVGSGSTHHVSSAATRKHLPGTGS 680 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Dyrk2 | NP_001260456.1 | PKc_DYRK4 | 186..529 | CDD:271127 | 161/376 (43%) |
S_TKc | 233..529 | CDD:214567 | 145/321 (45%) | ||
DYRK1B | NP_004705.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 67..89 | 2/21 (10%) | |
Bipartite nuclear localization signal. /evidence=ECO:0000255 | 69..86 | 2/16 (13%) | |||
PKc_DYRK1 | 97..436 | CDD:271128 | 148/340 (44%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 380..399 | 1/18 (6%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 436..629 | 34/167 (20%) | |||
Interaction with RANBP9. /evidence=ECO:0000269|PubMed:14500717 | 480..520 | 13/99 (13%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0667 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R968 |
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.840 |