Protein Alignment Dyrk2 and Doa

DIOPT Version :9

• Sequence 1: NP_001260456.1
• Gene: Dyrk2 / 34831
• FlyBaseID: FBgn0016930
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: NP_001014681.2
• Gene: Doa / 43415
• FlyBaseID: FBgn0265998
• Length: 2045
• Species: Drosophila melanogaster
• Alignment Length: 514
• Identity: 135/514 - (26%)
• Similarity: 224/514 - (43%)
• Gaps: 112/514 - (21%)

  Fly    92 SLNGNGNGNG----NSNSNNNNNIGSPVSSSTTNSSNGGNERGSSTKSNSSSGSGSSGNSASSTG 152
            |..|.|.|..    :.|:|......||.|||:........::....:|..     ...||.....
  Fly  1581 SAGGGGGGAAGLQYDPNTNTQLFYASPASSSSNKQPQQPQQQQQQQQSQL-----QQSNSVIFNH 1640

  Fly   153 SGELKCNTPMTPSELVKKFRNYLTDLEFEELKVYKEVWYFGQHASKNYNKPAPTANTTNLGYDDD 217
            ||:.........:|:.|.    ...|.|.|..                 ||        :..||.
  Fly  1641 SGQQHQPHQQQQNEMSKS----ALGLHFIETA-----------------KP--------VIQDDA 1676

  Fly   218 NGNYKIIEH--DHIAFRYEILEVIGKGSFGQVIRALDHKTNTHVAIKIIRNKKRFLNQAVVELNI 280
            :|:  :|.|  |.:..||:|:..:|:|:||:|::..|.:.:..:|:|||:|.:::...|.:|:|.
  Fly  1677 DGH--LIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDYCMALKIIKNVEKYREAAKLEINA 1739

  Fly   281 LDELREKDADGSHNVIHMLDYTYFRKHLCITFELMSLNLYELIKKNNYNGFSMSLIRRFCNSIVK 345
            |:::.:||....|..:.|:|:..:..|:||.||::.|::::.:::|||..:.:..:|.....:..
  Fly  1740 LEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCY 1804

  Fly   346 CLRLLYKENIIHCDLKPENIL-----------------LKQRGSSSIKVIDFGSSCYVDRKIYTY 393
            .::.|:...:.|.||||||||                 :::..::.:::|||||:.:......|.
  Fly  1805 SVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTI 1869

  Fly   394 IQSRFYRSPEVILGLQYGTAIDMWSLGCILAELYTGFPLFPGENEVEQLACIMEVLGLPPKVLIS 458
            :.:|.||:|||||.|.:....|:||:||||.|||.|..||...:..|.||.:..:||..|   ..
  Fly  1870 VSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIP---YR 1931

  Fly   459 VARRRRLFFDSRDAPRCITNTK---------GRKRSPGSKSLAHIL------------HCQDRYF 502
            :||...|:..        |.||         ..|.|.|.....|..            ||:   .
  Fly  1932 MARNHTLYSK--------TKTKYFYHGKLDWDEKSSAGRYVRDHCKPLFLCQLSDSEDHCE---L 1985

  Fly   503 IDFLQRCLEWDPAERMTPDEAAHHEF------------------LQPSASSRHRSCRMS 543
            ...:::.||::|:.|:|..||.||.|                  |...:|||.||..:|
  Fly  1986 FSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHRVGEVSNKQPLSSGSSSRERSHSLS 2044

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk2	NP_001260456.1	PKc_DYRK4	186..529	CDD:271127	107/400 (27%)
		S_TKc	233..529	CDD:214567	98/351 (28%)
Doa	NP_001014681.2	PKc_CLK	1679..2012	CDD:271036	101/348 (29%)
		S_TKc	1692..2012	CDD:214567	97/333 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460710
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740