Protein Alignment Dyrk2 and clk4a

DIOPT Version :9

• Sequence 1: NP_001260456.1
• Gene: Dyrk2 / 34831
• FlyBaseID: FBgn0016930
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: XP_003199888.1
• Gene: clk4a / 321857
• ZFINID: ZDB-GENE-030131-576
• Length: 496
• Species: Danio rerio
• Alignment Length: 346
• Identity: 114/346 - (32%)
• Similarity: 181/346 - (52%)
• Gaps: 28/346 - (8%)

  Fly   215 DDDNGNYKIIEHDHIAFRYEILEVIGKGSFGQVIRALDH-KTNTHVAIKIIRNKKRFLNQAVVEL 278
            ||:.|:......|.:..||||:..:|:|:||:|:..:|| |....:|:|||:|.:|:.:.|:.|:
Zfish   154 DDEEGHLVYHSGDMLRARYEIVCTLGEGAFGKVVECIDHEKVGARIALKIIKNIERYRDAALSEV 218

  Fly   279 NILDELREKDADGSHNVIHMLDYTYFRKHLCITFELMSLNLYELIKKNNYNGFSMSLIRRFCNSI 343
            .:|:::...|.|..:..:.|.|:.....|:||.|||:.|:.|:.:|:||:..|.::.||.....|
Zfish   219 EVLEQINSLDCDRRYACVRMYDWFDHHGHICIAFELLGLSTYDFLKENNFQPFYINHIRHMAYQI 283

  Fly   344 VKCLRLLYKENIIHCDLKPENILL-----------------KQRGSSSIKVIDFGSSCYVDRKIY 391
            ::.:|.|:|..:.|.||||||||.                 :...:..:||:|||::.|......
Zfish   284 IRAVRFLHKNKLTHTDLKPENILFVNSEYNIRYNSKMKRDERTVKNPDVKVVDFGNATYEHEHHT 348

  Fly   392 TYIQSRFYRSPEVILGLQYGTAIDMWSLGCILAELYTGFPLFPGENEVEQLACIMEVLGLPPKVL 456
            :.:.:|.||:|||||.|.:..:.|:||:||||.|.|.|..||...:..|.||.:..|||..|..:
Zfish   349 SVVSTRHYRAPEVILDLGWSHSCDVWSVGCILIEYYLGSTLFQTHDSKEHLAMMERVLGPIPTHM 413

  Fly   457 ISVARRRRLFFDSRDAPRCITNTKGRKRSPGSKSLAHIL------HCQDRYFIDFLQRCLEWDPA 515
            :...|:.| |..:......|.::.||......|.|...|      |.|   ..|.::|.||:|..
Zfish   414 LQKTRKSR-FVRNDKLDWDIHSSSGRYVRKQCKPLRQYLVSSSSDHEQ---LFDLIERMLEYDVT 474

  Fly   516 ERMTPDEAAHHEFLQPSASSR 536
            :|:|.|||..|.|......|:
Zfish   475 KRITLDEAIKHPFFNSIRKSK 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk2	NP_001260456.1	PKc_DYRK4	186..529	CDD:271127	112/337 (33%)
		S_TKc	233..529	CDD:214567	107/319 (34%)
clk4a	XP_003199888.1	PKc_like	159..488	CDD:304357	109/332 (33%)
		S_TKc	172..488	CDD:214567	107/319 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810