Protein Alignment Dyrk2 and Clk1

DIOPT Version :9

• Sequence 1: NP_001260456.1
• Gene: Dyrk2 / 34831
• FlyBaseID: FBgn0016930
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: NP_001100383.2
• Gene: Clk1 / 301434
• RGDID: 1311469
• Length: 483
• Species: Rattus norvegicus
• Alignment Length: 430
• Identity: 138/430 - (32%)
• Similarity: 206/430 - (47%)
• Gaps: 68/430 - (15%)

  Fly   128 ERGSSTKSNSSSGSGSSGNSASSTGSGELKCNTPMTPSELVKKFRNYLTDLEFEELKVYKEVWYF 192
            |.||..:::||..||.||.|:                                     ||.....
  Rat    91 EPGSRYQNHSSKSSGRSGRSS-------------------------------------YKSKHRS 118

  Fly   193 GQHAS--KNYNKPAPTANTTNLGYDDDNGNYKIIEHDHIAFRYEILEVIGKGSFGQVIRALDHKT 255
            ..|.|  :::.|......:.:: .||:.|:......|.::.||||::.:|:|:||:|:..:|||.
  Rat   119 HHHTSHRRSHGKSHRRKRSRSV-EDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKV 182

  Fly   256 -NTHVAIKIIRNKKRFLNQAVVELNILDELREKDADGSHNVIHMLDYTYFRKHLCITFELMSLNL 319
             ..|||:||::|..|:...|..|:.:|:.|...|...:...:.||::...|.|:||.|||:.|:.
  Rat   183 GGRHVAVKIVKNVDRYCEAAQSEIQVLEHLNATDPHSTFRCVQMLEWFEHRGHICIVFELLGLST 247

  Fly   320 YELIKKNNYNGFSMSLIRRFCNSIVKCLRLLYKENIIHCDLKPENILLKQRG------------- 371
            |:.||:|::..|.|..||:....|.|.:..|:...:.|.||||||||..:..
  Rat   248 YDFIKENSFLPFRMDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVKSDYTEAYNPKMKRDE 312

  Fly   372 ----SSSIKVIDFGSSCYVDRKIYTYIQSRFYRSPEVILGLQYGTAIDMWSLGCILAELYTGFPL 432
                :..|||:||||:.|.|....|.:.:|.||:|||||.|.:....|:||:||||.|.|.||.:
  Rat   313 RTIVNPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTV 377

  Fly   433 FPGENEVEQLACIMEVLGLPPKVLISVARRRRLFFDSR---DAPRCITNTKGRKRSPGSKSLAHI 494
            ||..:..|.||.:..:||..||.:|...|:|..|...|   |.    .::.||..|...|.|...
  Rat   378 FPTHDSREHLAMMERILGPLPKHMIEKTRKRTYFHHDRLDWDE----HSSAGRYVSRRCKPLKEF 438

  Fly   495 LHCQD---RYFIDFLQRCLEWDPAERMTPDEAAHHEFLQP 531
            :..||   ....|.:.:.||:|||:|:|..||..|.|..|
  Rat   439 MLSQDAEHELLFDLIGKMLEYDPAKRITLKEALKHPFFYP 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk2	NP_001260456.1	PKc_DYRK4	186..529	CDD:271127	126/368 (34%)
		S_TKc	233..529	CDD:214567	116/319 (36%)
Clk1	NP_001100383.2	PKc_CLK1_4	147..476	CDD:271115	118/332 (36%)
		S_TKc	160..476	CDD:214567	116/319 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810