Protein Alignment Dyrk2 and Clk4

DIOPT Version :9

• Sequence 1: NP_001260456.1
• Gene: Dyrk2 / 34831
• FlyBaseID: FBgn0016930
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: XP_038941309.1
• Gene: Clk4 / 287269
• RGDID: 1310274
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 342
• Identity: 116/342 - (33%)
• Similarity: 179/342 - (52%)
• Gaps: 36/342 - (10%)

  Fly   215 DDDNGNYKIIEHDHIAFRYEILEVIGKGSFGQVIRALDH-KTNTHVAIKIIRNKKRFLNQAVVEL 278
            ||:.|:......|.:..||||::.:|:|:||:|:..:|| ....|||:||::|..|:...|..|:
  Rat   167 DDEEGHLICQSGDVLRARYEIVDTLGEGAFGKVVECIDHGMDGLHVAVKIVKNVGRYREAARSEI 231

  Fly   279 NILDELREKDADGSHNVIHMLDYTYFRKHLCITFELMSLNLYELIKKNNYNGFSMSLIRRFCNSI 343
            .:|:.|...|.:.....:.||::.....|:||.|||:.|:.|:.||:|::..|.:..||:....|
  Rat   232 QVLEHLNSTDPNSVFRCVQMLEWFDHHGHVCIVFELLGLSTYDFIKENSFLPFQIDHIRQMAYQI 296

  Fly   344 VKCLRLLYKENIIHCDLKPENILL-----------------KQRGSSSIKVIDFGSSCYVDRKIY 391
            .:.:..|:...:.|.||||||||.                 :...::.|||:||||:.|.|....
  Rat   297 CQSINFLHHNKLTHTDLKPENILFVKSDYVVKYNSKMKRDERTLKNTDIKVVDFGSATYDDEHHS 361

  Fly   392 TYIQSRFYRSPEVILGLQYGTAIDMWSLGCILAELYTGFPLFPGENEVEQLACIMEVLGLPPKVL 456
            |.:.:|.||:|||||.|.:....|:||:||||.|.|.||.:|...:..|.||.:..:||..|..:
  Rat   362 TLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFQTHDSKEHLAMMERILGPIPAHM 426

  Fly   457 ISVARRRRLFFDSR-------DAPRCITNTKGRKRSPGSKSLAHILHCQD---RYFIDFLQRCLE 511
            |...|:|:.|..::       .|.|.:     |:|   .|.|...:.|.|   ....|.::|.||
  Rat   427 IQKTRKRKYFHHNQLDWDEHSSAGRYV-----RRR---CKPLKEFMLCHDEEHEKLFDLVRRMLE 483

  Fly   512 WDPAERMTPDEAAHHEF 528
            :||.:|:|.|||..|.|
  Rat   484 YDPTKRITLDEALQHPF 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk2	NP_001260456.1	PKc_DYRK4	186..529	CDD:271127	116/342 (34%)
		S_TKc	233..529	CDD:214567	111/324 (34%)
Clk4	XP_038941309.1	PKc_CLK1_4	172..501	CDD:271115	113/337 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810