Protein Alignment Dyrk2 and prpf-4

DIOPT Version :9

• Sequence 1: NP_001260456.1
• Gene: Dyrk2 / 34831
• FlyBaseID: FBgn0016930
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: NP_001250391.1
• Gene: prpf-4 / 172443
• WormBaseID: WBGene00004186
• Length: 775
• Species: Caenorhabditis elegans
• Alignment Length: 585
• Identity: 144/585 - (24%)
• Similarity: 244/585 - (41%)
• Gaps: 128/585 - (21%)

  Fly    37 DLVWCPGIQLDNEKLRRDVRLSGSRLDLPQLCNGSRRLDGHNNHVAANENTVTTTSLNGNGNGNG 101
            |:.|    .||::......::..:|....|:.   ::::||     ..|||..
 Worm   220 DVEW----NLDSDSDDEQKKIEAARKRRIQII---KKIEGH-----TEENTPR------------ 260

  Fly   102 NSNSNNNNNIGSPVSSSTTNSSNGGNERGSSTKSNSSSGSGSSGNSASSTGSGELKCNTPM---- 162
            :|::..::.||...:..:.:||:...:.....|...:.....|....|..|||   .:||:
 Worm   261 DSSTPRSDTIGDKKTDESEDSSSDSEDDEDDRKLAEAKDLIKSTRFGSEQGSG---ASTPVSIQS 322

  Fly   163 ---TPSELVKKFRNYLTDL-EFEELKV-----------YKEVWY--------------------- 191
               ||::.....|:.:..: :.:|..|           |:|.|:
 Worm   323 DNDTPTDFFSGLRDKMVHMKDADEHNVDEVLQRGKDEEYREDWHTQLKEQEKREEEEKKKKLEAE 387

  Fly   192 -FGQHASKNY-------------NKPAPTANTTNLG------------YDDDNGNYKIIEHDHIA 230
             ..:.|.|..             |:..|..:||..|            :||..|.|::...:.:.
 Worm   388 AAAEAAKKKKQEEDDTGFDMFADNEELPQDSTTIDGHSGAVHDTLKDNWDDVEGYYRVRIGELLD 452

  Fly   231 FRYEILEVIGKGSFGQVIRALDHKTNTHVAIKIIRNKKRFLNQAVVELNILDELREKDADGSHNV 295
            .||.::...|.|.||.|.|..|......||:|||||.:......:.||.:|.:|.|.|.:..::.
 Worm   453 TRYRVVGFTGAGVFGNVCRCNDQTKGNTVAVKIIRNNEVMYKTGLRELEVLRKLNEADKEDKYHC 517

  Fly   296 IHMLDYTYFRKHLCITFELMSLNLYELIKK-NNYNGFSMSLIRRFCNSIVKCLRLLYKENIIHCD 359
            :.:........|||:.||.:|:||.||:|| ...:|..:..:|.:...::..||||.|...:|.|
 Worm   518 LRLFRTFKHHNHLCLVFENLSMNLRELLKKYGQKDGLHLKAVRSYAQQLLLALRLLKKLEFVHAD 582

  Fly   360 LKPENILLKQRGSSSIKVIDFGSSCYV-DRKIYTYIQSRFYRSPEVILGLQYGTAIDMWSLGCIL 423
            :||:|||:.: ...::|:.||||:..| ::::..|:.|||||:||::||:::..|||:||:...|
 Worm   583 IKPDNILVNE-SKLTLKLCDFGSAGRVNEQELAPYLVSRFYRAPEIMLGVRHDYAIDLWSVAVTL 646

  Fly   424 AELYTGFPLFPGENEVEQLACIMEVLGLPPKVLISVARRRRLFFD--------------SRDAPR 474
            .|:|||..:|||......|....:|.|..|..|:..::.:...||              .|:...
 Worm   647 YEVYTGKIMFPGRTNNHMLKLFTDVKGKYPNKLVRKSQFKDTHFDVNCNLLYQEVDKVTERNKIT 711

  Fly   475 CITNTK-----------GRKRSPGSKSLAHILHCQDRYFIDFLQRCLEWDPAERMTPDEAAHHEF 528
            .:.|.|           |::.|.....       |.:.|...|...|..||::|.|.:||..|.|
 Worm   712 VLANLKPTRDLESELIAGQRLSRDQMD-------QIQAFRTLLDGMLILDPSKRTTCNEALKHPF 769

  Fly   529  528
             Worm   770  769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk2	NP_001260456.1	PKc_DYRK4	186..529	CDD:271127	115/417 (28%)
		S_TKc	233..529	CDD:214567	100/323 (31%)
prpf-4	NP_001250391.1	STKc_PRP4	454..770	CDD:271037	101/324 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D870358at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920