Protein Alignment Dyrk2 and C16A11.10

DIOPT Version :9

• Sequence 1: NP_001260456.1
• Gene: Dyrk2 / 34831
• FlyBaseID: FBgn0016930
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: NP_001254087.1
• Gene: C16A11.10 / 13184588
• WormBaseID: WBGene00185089
• Length: 385
• Species: Caenorhabditis elegans
• Alignment Length: 381
• Identity: 92/381 - (24%)
• Similarity: 162/381 - (42%)
• Gaps: 85/381 - (22%)

  Fly   215 DDDN--GNYKIIEHDHI----AFRYEILEVIGKGSFGQVIRALDHKTNTHVAIKIIRN------- 266
            |::|  ||.:.:..:.|    ..:.:|:..:|:|.||.|.:.:|| :|...|:|:.:.
 Worm    25 DNENVAGNRENLPKNPILTSSGAQLKIIAKLGEGVFGAVYKVVDH-SNKKYAVKLFKEEHSEVGE 88

  Fly   267 ----KKRFLNQAVVELNILDELREKDADGSHNVIHMLDYTYFRKHLCITFELMSLNLYELIKKNN 327
                ::..:.:||..:|..:.:|.:|   |..:...:...:.:  :.|:|||...:::|::....
 Worm    89 QSWARETAIMKAVTAINSANLIRMED---SWRINESVPNGFLK--IAISFELKGRSVFEVMDSTK 148

  Fly   328 YN-------GFSMSLIRRFCNSIVKCLRLLYKENIIHCDLKPENILLKQRGSSSIKVIDFGSSCY 385
            ..       .|.::.||.....:::.:..|....|:|.|||||||...  .|.:.|....|:.|:
 Worm   149 GKMPAGSEISFEINAIRVMGKQLLEAMEKLESVKIVHLDLKPENICFS--SSCTFKTTVTGNVCF 211

  Fly   386 VDRKI---------------------YTYIQSRFYRSPEVILGLQYGTAIDMWSLGCILAELYTG 429
            :...|                     |..:|::.||:||:.|||.:....|:||.||||:|||||
 Worm   212 IQPSIFHVCVVDFGNARTIRQDKPPKYALVQTQNYRAPEIFLGLPFSVKSDIWSFGCILSELYTG 276

  Fly   430 FPLFPG----ENEVEQLACIMEVLGLPPKVLISVARRRRLFFDSRDAPRCITNTKGR-------- 482
            ..||.|    :.|..|...:..::..||...:           .|:|.: |.:||.|
 Worm   277 DLLFYGNSKSDTEELQFELMQMIVQQPPSCAM-----------LREAEK-IKSTKIRIENGNVYM 329

  Fly   483 -KRSPGSKSLAHILHCQDR-------YFIDFLQRCLEWDPAERMTPDEAAHHEFLQ 530
             ::|..|......||.|.|       ...|.|:..|..||:.|.:..:.:...|.:
 Worm   330 KRKSKSSFEPPKPLHKQRRPKDLEAIPLFDLLECILIVDPSRRPSLRDISSRTFFK 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk2	NP_001260456.1	PKc_DYRK4	186..529	CDD:271127	91/378 (24%)
		S_TKc	233..529	CDD:214567	86/354 (24%)
C16A11.10	NP_001254087.1	PKc_like	50..384	CDD:389743	86/353 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163637
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740