Protein Alignment Dyrk2 and Clk4

DIOPT Version :9

• Sequence 1: NP_001260456.1
• Gene: Dyrk2 / 34831
• FlyBaseID: FBgn0016930
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: XP_017169732.1
• Gene: Clk4 / 12750
• MGIID: 1098551
• Length: 510
• Species: Mus musculus
• Alignment Length: 406
• Identity: 127/406 - (31%)
• Similarity: 198/406 - (48%)
• Gaps: 67/406 - (16%)

  Fly   172 RNYLTDLEFEELKVYKEVWYFGQHASKN------------YNKPAPTANTTNLGY---------D 215
            |:|..|:|    ..|:      .|.||:            .|:|..:..:.:..:         |
Mouse   116 RHYHRDVE----STYR------IHCSKSSVRSRRSSPKRKRNRPCASHQSHSKSHRRKRSRSIED 170

  Fly   216 DDNGNYKIIEHDHIAFRYEILEVIGKGSFGQVIRALDH-KTNTHVAIKIIRNKKRFLNQAVVELN 279
            |:.|:......|.:..||||::.:|:|:||:|:..:|| ....|||:||::|..|:...|..|:.
Mouse   171 DEEGHLICQSGDVLRARYEIVDTLGEGAFGKVVECIDHGMDGLHVAVKIVKNVGRYREAARSEIQ 235

  Fly   280 ILDELREKDADGSHNVIHMLDYTYFRKHLCITFELMSLNLYELIKKNNYNGFSMSLIRRFCNSIV 344
            :|:.|...|.:.....:.||::.....|:||.|||:.|:.|:.||:|::..|.:..||:....|.
Mouse   236 VLEHLNSTDPNSVFRCVQMLEWFDHHGHVCIVFELLGLSTYDFIKENSFLPFQIDHIRQMAYQIC 300

  Fly   345 KCLRLLYKENIIHCDLKPENILL-----------------KQRGSSSIKVIDFGSSCYVDRKIYT 392
            :.:..|:...:.|.||||||||.                 :...::.|||:||||:.|.|....|
Mouse   301 QSINFLHHNKLTHTDLKPENILFVKSDYVVKYNSKMKRDERTLKNTDIKVVDFGSATYDDEHHST 365

  Fly   393 YIQSRFYRSPEVILGLQYGTAIDMWSLGCILAELYTGFPLFPGENEVEQLACIMEVLGLPPKVLI 457
            .:.:|.||:|||||.|.:....|:||:||||.|.|.||.:|...:..|.||.:..:||..|..:|
Mouse   366 LVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFQTHDSKEHLAMMERILGPIPAHMI 430

  Fly   458 SVARRRRLFFDSR-------DAPRCITNTKGRKRSPGSKSLAHILHCQD---RYFIDFLQRCLEW 512
            ...|:|:.|..::       .|.|.:     |:|   .|.|...:.|.|   ....|.::|.||:
Mouse   431 QKTRKRKYFHHNQLDWDEHSSAGRYV-----RRR---CKPLKEFMLCHDEEHEKLFDLVRRMLEY 487

  Fly   513 DPAERMTPDEAAHHEF 528
            |||.|:|.|||..|.|
Mouse   488 DPARRITLDEALQHPF 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk2	NP_001260456.1	PKc_DYRK4	186..529	CDD:271127	123/392 (31%)
		S_TKc	233..529	CDD:214567	112/324 (35%)
Clk4	XP_017169732.1	PKc_CLK1_4	175..504	CDD:271115	114/337 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810