Protein Alignment Dyrk2 and dyrk3

DIOPT Version :9

• Sequence 1: NP_001260456.1
• Gene: Dyrk2 / 34831
• FlyBaseID: FBgn0016930
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: NP_001108400.1
• Gene: dyrk3 / 100141364
• ZFINID: ZDB-GENE-080219-31
• Length: 581
• Species: Danio rerio
• Alignment Length: 480
• Identity: 233/480 - (48%)
• Similarity: 304/480 - (63%)
• Gaps: 48/480 - (10%)

  Fly    93 LNGNGNGNGNSNSNNNNNIGSPVSSSTTNSSNGGNERGSSTKSNSSSGSGSSGNSASSTGSGELK 157
            |||....||.|.        .|.......|    .||  |..||||..|..|....:..||
Zfish    84 LNGVSQHNGTSQ--------VPAKPPPAIS----KER--SVDSNSSVKSSESSTKVTKLGS---- 130

  Fly   158 CNTPMTPSELVKKFRNYLTDLEFEELKVYKEVWYFGQHASKNYNKPAPTANTTNLGYDDDNGNYK 222
               ||||.:.:|:.|..:|.||.:|:..|.|:::.|.:|.|   :.|....|.|.|||||.|.|.
Zfish   131 ---PMTPEQALKQHRQQMTTLEQQEIHNYSEIYFLGPNAKK---RQAVAGGTNNSGYDDDQGGYI 189

  Fly   223 IIEHDHIAFRYEILEVIGKGSFGQVIRALDHKTNTHVAIKIIRNKKRFLNQAVVELNILDELREK 287
            .:.|||:|:|||.|:||||||||||.:..|||...|||:||:||:|||..||..|:.||:.|:::
Zfish   190 HVPHDHLAYRYEFLKVIGKGSFGQVAKVYDHKLQQHVALKIVRNEKRFHRQAAEEIRILEHLKKQ 254

  Fly   288 DADGSHNVIHMLDYTYFRKHLCITFELMSLNLYELIKKNNYNGFSMSLIRRFCNSIVKCLRLLYK 352
            |..||.||:|||:...||.|:|:||||:|:|||||||:|.:.|||:.|:|:|.:||::||..|::
Zfish   255 DKTGSMNVVHMLENFTFRNHICMTFELLSMNLYELIKRNKFQGFSLPLVRKFAHSILQCLEALHR 319

  Fly   353 ENIIHCDLKPENILLKQRGSSSIKVIDFGSSCYVDRKIYTYIQSRFYRSPEVILGLQYGTAIDMW 417
            ..|||||||||||||||:|.|.||||||||||:..:::||||||||||:||||||.:||..||||
Zfish   320 HKIIHCDLKPENILLKQQGRSGIKVIDFGSSCFDHQRVYTYIQSRFYRAPEVILGSRYGMPIDMW 384

  Fly   418 SLGCILAELYTGFPLFPGENEVEQLACIMEVLGLPPKVLISVARRRRLFFDSRDAPR-CITNT-- 479
            |.|||||||.||:||||||:|.:||||:||:||:||..|:..|:|.:.|..|:..|| |..:|
Zfish   385 SFGCILAELLTGYPLFPGEDEGDQLACMMELLGMPPSKLLEQAKRAKNFISSKGHPRYCTVSTLS 449

  Fly   480 ------------KGRKR-SPGSKSLAHILH-CQDRYFIDFLQRCLEWDPAERMTPDEAAHHEFL- 529
                        :|:.| :||||.....|. |:|..|||||::||:|||:.||||.:|..|.:|
Zfish   450 NGTIVLNGSRSRRGKMRGAPGSKEWGTALKGCEDATFIDFLKKCLDWDPSTRMTPVQALRHPWLY 514

  Fly   530 ------QPSASSRHRSCRMSSSSSS 548
                  .|.........|:|..|:|
Zfish   515 KRLPKPAPGGEKTVLPKRISEHSTS 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk2	NP_001260456.1	PKc_DYRK4	186..529	CDD:271127	198/359 (55%)
		S_TKc	233..529	CDD:214567	178/312 (57%)
dyrk3	NP_001108400.1	PKc_DYRK2_3	134..513	CDD:271126	205/381 (54%)
		S_TKc	200..513	CDD:214567	178/312 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162948at33208
OrthoFinder	1	1.000	-	-		FOG0000895
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100394
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X888
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.720