DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43333 and Postn

DIOPT Version :9

Sequence 1:	NP_788051.1	Gene:	CG43333 / 34830	FlyBaseID:	FBgn0263038	Length:	1166	Species:	Drosophila melanogaster
Sequence 2:	NP_001355607.1	Gene:	Postn / 50706	MGIID:	1926321	Length:	838	Species:	Mus musculus

Alignment Length:	276	Identity:	74/276 - (26%)
Similarity:	116/276 - (42%)	Gaps:	46/276 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   899 QSGLDSILNETGPYTIFVPTDKAFKNLLVQLGGPERAEEKFQSNPRLLSGLLLHHVIPGAFEIAT 963
            |.||.|.|...|.||:..|.:.||            :::....:.|||..:|.:|::.....::.
Mouse   392 QLGLASSLKPDGEYTLLAPVNNAF------------SDDTLSMDQRLLKLILQNHILKVKVGLSD 444

  Fly   964 LQDEMTGVSLAGTQLRVNQYNMHDQEWNDVTLTTINGAMVVLNKKDIKIPQGVAHAVDRVMFPLP 1028
            |.:.....::.|.||||..|.         |...|..:.:|...|..:  .|..|....::.|..
Mouse   445 LYNGQILETIGGKQLRVFVYR---------TAICIENSCMVRGSKQGR--NGAIHIFREIIQPAE 498

  Fly  1029 VGDILQTLQSDREGRFSNFLKILYTSGLSEKLQSKGVKTYTVFAPVDKSFSELDSDTLEKLYNDK 1093
             ..:...|:.|:  |||.||.:|..:.|.:.|...|  .:|:|||.:.:|..:.|:..|.|..||
Mouse   499 -KSLHDKLRQDK--RFSIFLSLLEAADLKDLLTQPG--DWTLFAPTNDAFKGMTSEERELLIGDK 558

  Fly  1094 DTAEQFAMKHIVPGALFSAGMRFYQVKDSLSTGKTVILQKTSAGKI---------KVNDAQMVTS 1149
            :..:...:.|:.||.....|         ...|.|.||:.|...||         .||:.:...|
Mouse   559 NALQNIILYHLTPGVYIGKG---------FEPGVTNILKTTQGSKIYLKGVNETLLVNELKSKES 614

  Fly  1150 NIPATNGVIHALDGVL 1165
            :|..||||||.:|.:|
Mouse   615 DIMTTNGVIHVVDKLL 630

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43333	NP_788051.1	FAS1	844..1026	CDD:225214	29/126 (23%)
		Fasciclin	889..1026	CDD:280607	29/126 (23%)
		Fasciclin	1042..1165	CDD:280607	41/131 (31%)
Postn	NP_001355607.1	Fasciclin	111..232	CDD:308211
		Fasciclin	247..369	CDD:308211
		Fasciclin	384..496	CDD:308211	29/126 (23%)
		Fasciclin	509..632	CDD:308211	42/135 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	811..838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	61	1.000	Domainoid score	I10498
eggNOG	1	0.900	-	-		E1_COG2335
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100594
Panther	1	1.100	-	-	O	PTHR10900
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.770