Protein Alignment CG46301 and NOL4

DIOPT Version :9

• Sequence 1: NP_001334737.1
• Gene: CG46301 / 34829
• FlyBaseID: FBgn0283651
• Length: 1237
• Species: Drosophila melanogaster
• Sequence 2: NP_001371396.1
• Gene: NOL4 / 8715
• HGNCID: 7870
• Length: 661
• Species: Homo sapiens
• Alignment Length: 1202
• Identity: 291/1202 - (24%)
• Similarity: 403/1202 - (33%)
• Gaps: 582/1202 - (48%)

  Fly    73 AEREIIYELFQPWALSTYGDQAKTKTITLRKKARILKALEGKEHSRPDSSKFRFWVKTKGFTTNR 137
            :||: :|..||.|.|.||||..||||:|.:|..||::.|.|.|.|..|::||:||||:|||...:
Human     3 SERD-MYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGSESSSTDNAKFKFWVKSKGFQLGQ 66

  Fly   138 PEGFEEAPGSRRHLKNLPSSAILSDNPADVDLFAASTSKGFG---RRTYRKVACVEEFFDIIYNV 199
            |:......|..:.:..:|                ..|:.|.|   :.:.|:||.||:||||||::
Human    67 PDEVRGGGGGAKQVLYVP----------------VKTTDGVGVDEKLSLRRVAVVEDFFDIIYSM 115

  Fly   200 HMELGGRSGM---HAGQKRTYRI-----------------------ITETYAFLPREAVTRFLTI 238
            |:|.|.....   ||||||||:.                       |:|:|||||||||||||..
Human   116 HVETGPNGEQIRKHAGQKRTYKAPLEPPLYSTLSFYEFDFFNFHLQISESYAFLPREAVTRFLMS 180

  Fly   239 CPECKKNLRPSSPSGGGKDSDLAGNESSSEVENYLNYSSHTESSLEAGPTAKRRRHSSAEIKASL 303
            |.||:|.:. .:|.|                      :.|.::.
Human   181 CSECQKRMH-LNPDG----------------------TDHKDNG--------------------- 201

  Fly   304 ASGLAVGAGVASSMSATQLDVLWTGVPRSRSPKPPMAAEAAVE-TTPVSVPKIR-IKTQLQRPSS 366
                                            |||....:.:: ..|:::..:: :|.||.....
Human   202 --------------------------------KPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQ 234

  Fly   367 PQDQSPADPN----TDAQSQSQIQSQSQSQSQSQSQSHSQPSGQGFDAQLLKSRDNLLRYYNFMR 427
            .:|:|..:.:    :|:...|.:.|...|..:.:.||.....||..|       |:....:|
Human   235 DEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDD-------DSAAESFN--- 289

  Fly   428 RFYAGEPVLAPPIYGSSLLQSLSYPTTISTAATATPTTPTTTTSAPGKMLAPPKTATPPPNPPKI 492
                |...|     |.|           |.|:..|.:.....:::.||
Human   290 ----GNETL-----GHS-----------SIASGGTHSREMGDSNSDGK----------------- 317

  Fly   493 KTSPDSLLRARTPPVASTATSAAPKDAAHTPINLTKSLFSSLKTGHAPSTSTPVPLKLELPSPPK 557
                                :...:|  ..|:||:.|                 ||..:|
Human   318 --------------------TGLEQD--EQPLNLSDS-----------------PLSAQL----- 338

  Fly   558 PLPELRIPQLRGMPPVELSLPLPPLDLERLKPITSTYLQLTRSMGLSDEDALRFDNLETIPATPV 622
                                             ||.|               |.|:..:
Human   339 ---------------------------------TSEY---------------RIDDHNS------ 349

  Fly   623 VSTDTASVVGVGVGGGGGAAAGAGGGAGGAGGLLGDVVSGLGGGLVNESEAYAGLMKDADKLKLM 687
                                                                    ...:|.|.:
Human   350 --------------------------------------------------------NGKNKYKNL 358

  Fly   688 LLAWNYQNSTAVRNGTEGPDLSVVGGLWAQYQNALAQNAAAAAAASGKMDSSLSPVPRQDAHSPM 752
            |::.......|..||::.|..|     ::.|.             |||.:|             :
Human   359 LISDLKMEREARENGSKSPAHS-----YSSYD-------------SGKNES-------------V 392

  Fly   753 ETQDETNSSGQKEEDEVSEDDSDDKLDEKLATTH--DPERLKAFNMFVRLFVDENLDRIIPISKQ 815
            :...|..|..:.:|||...:|.||  .||:..|.  :.||||||||||||||||||||::|||||
Human   393 DRGAEDLSLNRGDEDEDDHEDHDD--SEKVNETDGVEAERLKAFNMFVRLFVDENLDRMVPISKQ 455

  Fly   816 PKEKIQAIIDSCARQFPEFSDRSRKRIRTYLKSCRRNKKTRDGWENTTRPTPAHLTSVQAEQILA 880
            ||||||||||||.|||||:.:|:|||||||||||||.|  |.|:| .:||.|:||||..||.|||
Human   456 PKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMK--RSGFE-MSRPIPSHLTSAVAESILA 517

  Fly   881 IACENESMN-AKRMRIGLEPITHAVPAPGSAVAAAAAAAAAAAVVAATSSSAGGTSTTAAGNATA 944
            .|||:||.| |||||:..:. ..:.||.......|.
Human   518 SACESESRNAAKRMRLERQQ-DESAPADKQCKPEAT----------------------------- 552

  Fly   945 TCGMGGVGDATGLTSAAAAALPFVSAVGFARSTPNSEHADVLPFGGAGTAGGSGGGGAGGGGGGG 1009
                    .||..|||                .|.|:  |||...|.||.......|.|||
Human   553 --------QATYSTSA----------------VPGSQ--DVLYINGNGTYSYHSYRGLGGG---- 587

  Fly  1010 MSSARSSPLALSSNASVSGGASVTGLTLANGAGASNGAGLPASSPYTTDFSSPSTASPFVAAAAA 1074
                    |...::||.||
Human   588 --------LLNLNDASSSG---------------------------------------------- 598

  Fly  1075 VAAGRAPSYPGYFPAVAGLGNVTPTDLSMKPTSGLGGNMVSNNNSNSSVTGNINSQLSAANLASL 1139
                                   |||||||      ..:.:::.|:||
Human   599 -----------------------PTDLSMK------RQLATSSGSSSS----------------- 617

  Fly  1140 SNASNNNALVTATQQLQQLQQQQQQQQQQQQQQQQQQLLVAGGGGMDGQSVRAPPILPHKLSANE 1204
               ||:..                                                   :||..|
Human   618 ---SNSRP---------------------------------------------------QLSPTE 628

  Fly  1205 VTAARQVISAYRESAAFLLRTADQVEQLLVQQ 1236
            :.|.||:::.||||||||||:||::|.|::||
Human   629 INAVRQLVAGYRESAAFLLRSADELENLILQQ 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46301	NP_001334737.1	None
NOL4	NP_001371396.1	MSCRAMM_ClfB	<231..400	CDD:411414	49/400 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	367	1.000	Domainoid score	I924
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	368	1.000	Inparanoid score	I2153
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003616
OrthoInspector	1	1.000	-	-		otm41508
orthoMCL	1	0.900	-	-		OOG6_106349
Panther	1	1.100	-	-	LDO	PTHR12449
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2493
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.960